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This is the first time scientists have successfully passed on a foreign gene to a future generation.
VOA: special.2009.06.23
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I could cut that up into fragments, and I could search in these fragments to try to find the one that has the insulin gene on it.
我把那部分切成碎片,然后从中找到有胰岛素基因的那一段
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We're cloning a gene of interest to us by sort of hijacking that biological mechanism by putting our gene on this plasmid and so our gene gets copied many times, as the plasmid gets copied many times.
我们克隆感兴趣的基因的做法,这个生物机制有点像是绑架,我们把基因绑在质粒身上,随着质粒被多次地复制,我们的基因也一起被多次复制
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This means they would pass on the gene for the green protein to their young.
VOA: special.2009.06.23
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So, Sal is convinced--he wants to be convinced; he desperately wants to be convinced--that Mississippi Gene knows Big Slim Hazard. Let's look at another example on page 59.
所以萨尔信服了，他想要被说服;,他极其渴望被说服，很愿意相信吉恩,认识细杆哈查德，让我们来看59页上的例子。
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Later,a male transgenic marmoset reproduced and passed on the green gene to a baby.
VOA: special.2009.06.23
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If this was a sickle patient, so they had this gene instead it wouldn't get cut and when I went to look for that presence of that gene on this gel, it would appear as one large segment instead of a large one and a smaller one.
而如果是个镰状红细胞贫血的病人,他们的基因是不会被限制酶切割的,因此他们基因的凝胶电泳结果就不会呈现,一大一小的结果,而只有一个大的片段
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They homed in on a single gene, known as GNPTAB, which was defective in 46 members of a large Pakistani family.
VOA: standard.2010.02.11
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If it's making the protein you want, it must be producing messenger RNA with that gene on it.
如果它正在制造你想要的蛋白质,它一定也在制造,你要的基因的mRNA
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In the life sciences, the journal's editors noted advances in gene therapy something that has long seemed on the verge of a breakthrough.
VOA: standard.2009.12.24
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When they make milk they have signals for turning on the betagalactoglobulin promoter and expressing the gene of interest.
泌乳的时候,β-乳球蛋白启动子受信号调控而开启,目的基因得以表达
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During's field is gene therapy, so he's working on a way to recreate that effect by modifying the gene that controls the leptin hormone.
VOA: standard.2010.07.14
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So this gene is going to be turned on in the sheep when it makes milk, under conditions where it makes milk.
这段基因会被激活,这段基因会在羊制造乳汁时被激活
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An article on the discovery of a gene associated with stuttering, and the commentary by Simon Fisher, are published this week in the New England Journal of Medicine.
VOA: standard.2010.02.11
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It's a gene that's on the plasmid, and this particular gene confers a specific biological property to cells that have the plasmid and can use it properly.
它是质粒自带的基因,如果细胞能够获得这种质粒,并正确的利用它的话,这段基因就能赋予该细胞某种生物学特性
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One key to breaking the current impasse on climate and energy legislation, says the League's Gene Karpinski, will be if the public demands stronger leadership from members of Congress and from the White House.
VOA: standard.2010.02.25
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It's on the gene for hemoglobin and the hemoglobin that you produce if you have sickle cell anemia is not quite right because there's one base difference.
这个缺陷基因和血红蛋白有关,如果你有镰状红细胞贫血症,那你所产生的血红蛋白就不太正常,因为这里有一个碱基不同
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Before we talk about how to do it-- and we don't have perfect ways to do it yet but I'll describe some of the ways that are used, I want to talk just briefly on this slide about what the goals for gene therapy might be.
在讲具体怎么做之前--,现在还没有任何一种方法是完美的,但我还是要讲讲一些已经应用的方法,我借助这张幻灯片简要介绍一下,基因治疗的可能目标
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I want you to look at this picture, read the little bit about gene - control of gene expression - that's in the book, know that it's a big topic, that we're not going to talk about it except we're going to talk about some examples where control of gene expression can be exploited in order to treat diseases, for example. So I'll see you on Thursday.
所以我希望你能看一下这张图,读一些,教材里基因调控的章节,这是个很大的话题,我们不会进一步深入去探讨,但一些基因调控,用以治疗疾病的例子,我们可能还会在之后的课程中讲到,那我们周四见了
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When this bound receptor interacts with DNA it could, for example, turn on expression of a target gene.
该受体与DNA结合后能够,启动目标基因的表达
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It's an example of a technology called a gene chip that allows you to, on each one of these spots there is DNA for example, that's specific for a particular gene in your genome, in the human genome for example.
这是一种叫做,基因芯片的技术,其上每个点可能代表着一种DNA,它是你基因组中一个特定的基因,亦或是人类基因组中的一个基因
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A section of DNA that is responsible for encoding a gene, let's say it's the insulin gene for example, might be some stretch of DNA on a certain chromosome inside your cells, inside the cells of the pancreas.
一段编码蛋白的DNA序列,我们就拿编码胰岛素的基因来举个例子,它也许是一段DNA基因序列,位于你胰腺细胞里的,某条染色体上
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