• The Royal Swedish Academy says the DNA in cells contains the designs for how people, plants and bacteria look and operate.

    VOA: special.2009.12.08

  • This is a much more efficient way to get DNA for a gene that you're interested for a couple of reasons.

    用这个办法能更有效率地获取你,感兴趣的基因的DNA,原因如下

    耶鲁公开课 - 生物医学工程探索课程节选

  • It's totally synthetic, there's no micro-organism involved in making the DNA for you, You can do it very rapidly in a laboratory, and fairly inexpensively now.

    完全是复制的过程,没有任何微生物参与制造DNA,你可以在实验室里迅速地进行,费用现在也相当便宜了

    耶鲁公开课 - 生物医学工程探索课程节选

  • The group said Congress should support large amounts of money for all areas of forensic science, not just DNA.

    VOA: special.2009.10.03

  • So this means we can code for it in DNA, you don't have to worry how am I going to get into the cell.

    这意味着我们可以在DNA中编写它,你不用担心它怎么进到细胞里去。

    麻省理工公开课 - 化学原理课程节选

  • The DNA of the flowering azalea plant,for example, contains all the information that makes it an azalea.

    VOA: special.2010.03.23

  • It's an example of a technology called a gene chip that allows you to, on each one of these spots there is DNA for example, that's specific for a particular gene in your genome, in the human genome for example.

    这是一种叫做,基因芯片的技术,其上每个点可能代表着一种DNA,它是你基因组中一个特定的基因,亦或是人类基因组中的一个基因

    耶鲁公开课 - 生物医学工程探索课程节选

  • He had shared a Nobel Prize for his part in the discovery of the structure of DNA.

    VOA: special.2010.03.23

  • So in the first week we run a section called from strawberries to gene therapy where we talk about DNA, extract DNA, you can play with the DNA of an organism and we can think about how to use DNA for other purposes.

    第一周组会的主题是从草莓到基因疗法,主要讨论DNADNA的提取,使你们对有机组织的DNA有直观的认识,并思考DNA的其它应用

    耶鲁公开课 - 生物医学工程探索课程节选

  • It found that except for nuclear DNA analysis, no forensic method has really proven itself as a way to link evidence to a person.

    VOA: special.2009.10.03

  • Retroviruses, for example, can only insert - can only transduce and express their DNA in cells that are dividing.

    就以逆转录病毒为例,它们只能在分裂阶段的细胞里,转导并表达自己的基因

    耶鲁公开课 - 生物医学工程探索课程节选

  • While DNA molecules contain the blueprint for life inside each cell of every organism, it is the ribosome that translates that information into life.

    VOA: standard.2009.10.07

  • If you have DNA fragments, so this is DNA that you've cut up into fragments using restriction enzymes for example.

    如果你有DNA片段,例如有一段你用限制酶,切割成片段的DNA

    耶鲁公开课 - 生物医学工程探索课程节选

  • I talked about just not using viruses but using plasmid DNA together with lipids and that's another strategy for gene therapy.

    这一部分我们不仅讲了病毒的应用,也讲了利用脂质体包裹的质粒DNA,基因治疗还有其它的策略

    耶鲁公开课 - 生物医学工程探索课程节选

  • They get arrested in the G1 phase, for example, and they never progress through to the S phase where they synthesize DNA.

    就比如说它们在G1期停滞不前,永远不能到达,合成DNA的S期

    耶鲁公开课 - 生物医学工程探索课程节选

  • When this bound receptor interacts with DNA it could, for example, turn on expression of a target gene.

    该受体与DNA结合后能够,启动目标基因的表达

    耶鲁公开课 - 生物医学工程探索课程节选

  • This might be a polio virus, for example. The example I've given here is a virus that contains DNA as its genetic material.

    例如 这个应该是,小儿麻痹症病毒,我曾在这里展示过,一种将DNA作为遗传物质的病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • There's one on DNA fingerprinting, for example, that gives you a little bit more detail about that specific technique; another one on production of therapeutic proteins.

    例如,这里有一段,是关于DNA指纹图谱法,提供了这项具体技术一些更详尽的细节,另一段是关于治疗性蛋白质的生产的

    耶鲁公开课 - 生物医学工程探索课程节选

  • Plasmids turn out to be one of the most powerful and simplest examples of a vector, what's called a vector for delivering DNA into a cell.

    质粒被证实是最强大,且最简单的载体形式之一,载体负责将DNA转入细胞

    耶鲁公开课 - 生物医学工程探索课程节选

  • They will reform their natural structure, and for DNA that means forming double helixes.

    它们将重新形成原本的结构,对于DNA来说,就是重新形成DNA双螺旋

    耶鲁公开课 - 生物医学工程探索课程节选

  • The receptor for estrogen is a special molecule called a DNA binding factor.

    雌激素受体是一类特殊的分子,叫做DNA结合因子

    耶鲁公开课 - 生物医学工程探索课程节选

  • The first step is we had to be able to take this circular DNA and cut it to create a site for our new gene to be added.

    第一步是切割环形DNA,以创造出一个整合新基因的位点

    耶鲁公开课 - 生物医学工程探索课程节选

  • Most restriction enzyme also recognize symmetric sequences of DNA, GAATTC for example.

    大多数限制性内切酶,也能识别DNA的对称序列,例如GAATTC

    耶鲁公开课 - 生物医学工程探索课程节选

  • This slide shows one important feature of the physical chemistry of DNA that turns out to be very important for all of the technology that is built on DNA.

    这张幻灯片展示了,DNA非常重要的理化特性,这些特性,对于所有以DNA为基础的技术很重要

    耶鲁公开课 - 生物医学工程探索课程节选

  • We want not only for the cell to be able to synthesize the DNA, you want it to be able to express the protein off the DNA as well.

    我们不仅希望细胞能复制DNA,还希望它能表达目标DNA所编码的蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • Then we'll talk about engineering of DNA and why this has been such - not only a rapidly growing and advancing area but one that's so important for Biomedical Engineering.

    然后我们会谈论DNA工程,以及为何它不仅,是一个向前飞速发展的领域,而且对生物医学工程十分的重要

    耶鲁公开课 - 生物医学工程探索课程节选

  • One is the processing has already been done so the introns are already out, so you don't have to figure out what's exon and what's the intron, it's already done for you.

    一是DNA已经过处理,内含子已经没有了,你不用分辨哪些是外显子哪些是内含子,这些都已经帮你做好了

    耶鲁公开课 - 生物医学工程探索课程节选

  • Let's talk about DNA synthesis for a minute.

    下面简要介绍一下DNA的合成

    耶鲁公开课 - 生物医学工程探索课程节选

  • When they separate, the primers that you've added automatically bind through the process of hybridization, and then you turn up the temperature to the optimum for Taq polymerase and DNA synthesis starts.

    当双链解旋后,加入的引物就会在杂交的步骤中自动,和解旋后的DNA结合,然后你再将温度升高至,Taq酶的最适温度,DNA就开始合成了

    耶鲁公开课 - 生物医学工程探索课程节选

  • You can say a polymer of DNA, for example, is four bases long, that means it has four of these repeat units and they go in the sequence from 5' to 3' of .

    打个比方,要描述一个由,四个核苷酸单位构成的寡聚DNA,就是说它由四个核苷酸单位构成,并且从5'端到3'端的顺序为

    耶鲁公开课 - 生物医学工程探索课程节选

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