Over the years,Mr.Saakashvili has consolidated power in the presidency to the detriment of the parliament.

VOA: standard.2009.09.01

Milton has invoked, of course to his own detriment--what was he thinking?

弥尔顿这么援引明显对己不利--他到底在想什么？

耶鲁公开课 - 弥尔顿课程节选

And in fact, in a TV series emotions are often seen as a detriment.

事实上，在电视剧中,拥有情感通常是弊端。

耶鲁公开课 - 心理学导论课程节选