One sort of opens up the beginning of life here and the other closes it down through a referencing of death.

前者讲的是生命的开始,后者通过诠释死亡,讲述了生命的终结

耶鲁公开课 - 聆听音乐课程节选

If a ligand comes and interacts with a receptor, it opens up; In the presence of this ligand, if the ligand goes away, it closes.

如果配体与受体相互作用,在配体存在的情况下通道打开,如果配体脱离,通道就关闭

耶鲁公开课 - 生物医学工程探索课程节选