The researchers knew it would be easier and less costly to map a smaller frog with fewer chromosomal pairs.

VOA: special.2010.06.29

You put this chromosomal DNA or this DNA that you're interested in, double stranded into a test tube.

你把这个染色体DNA,或者你感兴趣的双链的DNA,放进一个试管

耶鲁公开课 - 生物医学工程探索课程节选

How could I identify in a chromosomal DNA sample whether the sickle gene is present?

那我该怎么确定某染色体DNA样本中,是否存在这种致病基因呢

耶鲁公开课 - 生物医学工程探索课程节选

If I took this same restriction enzyme and tried to cut the chromosomal DNA of a sickle patient, it wouldn't cut at that point because the wrong sequence is there.

而如果我用同样的限制酶,去切割病人的染色体DNA,那该酶是不会起作用的,因为基因序列不对

耶鲁公开课 - 生物医学工程探索课程节选

We're going to take a chromosomal DNA, we're going to digest it with this restriction enzyme, we're going to put it in this tube and run it on a gel, and we're going to see what results down here.

我们取一条染色体DNA,然后用限制酶进行分解,接着再放,在凝胶上进行电泳,之后看看结果如何

耶鲁公开课 - 生物医学工程探索课程节选