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One of the things that happens is that certain cells within your body process the vaccine or the antigen and we talked about that.
在人体内,发生的反应之一是,特定的细胞对疫苗或者抗原做出反应,之前我们讨论过这个
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Then, your muscle cells would start producing Hepatitis B surface antigen and your immune system recognizing that's a foreign protein would start responding to it.
于是,肌肉细胞将会,开始制造乙肝表面抗原,然后免疫系统就会识别出,那是外来蛋白质并且产生免疫应答
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These are cells that recognize a particular antigen, they're ready to differentiate into antibody.
这些记忆细胞可识别相应的抗原,它们已经准备好分化产生抗体
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Usually the cellular means that they get rid of is that instead of an antibody being produced, you activate a population of cells that will specifically go and hunt down the foreign antigen, or more commonly, cells that contain the foreign antigen.
通常细胞免疫意味着,不用生成抗体就能清除抗原,你激活了一个细胞类群,这一类群能够,并杀伤外源抗原,或者更常见的是,杀伤含有外源抗原的细胞
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But this antigen presenting cell is more likely a professional antigen presenting cell, or a subset of cells of your immune system that are specialized in ingesting foreign particles and displaying their contents to the rest of the immune system.
但这种抗原呈递细胞更加类似于,专职抗原呈递细胞,或者是体内免疫细胞中的一个亚群,专门从事吞噬异己物质,并告知免疫系统的其他细胞的工作
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The other part of the adaptive immune system is the cell mediated immune system and this is an immune where that doesn't involve antibodies but involves cells that are activated in response to a foreign antigen and that utilize cellular means to get rid of it.
获得性免疫系统还包括,细胞免疫,这一免疫反应不包含抗体,但包含可以被激活来应答,并清除外源抗原的免疫细胞
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When these CD8 T-cells see your MHC1 together with an antigen that doesn't belong in you, it creates an immune response.
当CD8 T细胞识别MHC1时,同时识别了不属于你的抗原,由此产生免疫反应
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Helper cells don't become cytotoxic cells but they help B cells become antigen producing - antibody producing cells.
附助细胞不会成为细胞毒细胞,它们帮助B细胞成为抗体分泌细胞
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The antigen has to be presented to helper T-cells, those helper T-cells have to stimulate a B-cell population to both proliferate and differentiate.
抗原需要被呈递给辅助性T细胞,这些辅助性T细胞需要激活B淋巴细胞,使其增殖和分化
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These cells can now kill cells that have the correct signature, and the signature is MHC-1 with this foreign antigen associated with it.
而这些细胞现在可以杀伤带标记的细胞,这些标记就是MHC-1表面受体,和与其相联的异己抗原
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In this case here, you're generating host cells, cytotoxic T-cells, that can kill only very specific cells, cells that are expressing this foreign antigen.
而在这个例子中,人产生宿主细胞,即细胞毒性T细胞,它只会消灭特定的细胞,也就是携带特定异己抗原的细胞
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So, that's antigen presentation to this population of cells called cytotoxic T-cells, Tc, a subset of the class of T-cells in the immune system.
这些细胞被呈递给另一种细胞,这些细胞被称为细胞毒性T细胞,是免疫系统中T淋巴细胞的亚群中的一种
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They come from B-cells, they come from B-cells that are activated with a specific antigen.
抗体来自于B细胞,它们来自于被特别的抗原所激活的B细胞
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Because it has MHC-1, your MHC-1 on it, this T-cell recognizes that it's one of your cells but it has a foreign antigen associated with it.
因为该细胞上有MHC-1,T细胞将这些细胞识别为自身细胞,但这些细胞带有异己抗原
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The antibodies that are produced from these B-cells are also specific for the antigen.
产生自B细胞的抗体,对抗原来说是特异性的
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In the case of the helper cells they stimulate a specific population of B-cells to mature into antibody producing cells, and that antibody is generated against the antigen that stimulated it.
以辅助性T细胞为例,辅助性T细胞刺激特定的B细胞,使这些细胞成长为抗体分泌细胞,抗体分泌细胞产生大量的抗体,以消灭大量增殖的抗原
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