"The pollution issues are even more acute in the big urban areas,".

VOA: standard.2009.03.23

I lecture about what I like to talk about, what's interesting, that'll hopefully make you understand what the big issues are in all of this.

我讲我愿意讲的,有意思的,希望这些能让你明白,这里面都有什么大事件

耶鲁公开课 - 1871年后的法国课程节选

Especially on those big issues.

特别是在大问题上。

普林斯顿公开课 - 国际座谈会课程节选

"Overall,this will be a meeting about reaffirming the status quo, reaffirming the progress that's being made on lots of different issues, but not one with a big ambitious agenda."

VOA: standard.2010.05.17

What I'm looking for you to come away with when you read those scientific publications particularly, are the big picture issues.

我希望大家,特别在阅读这类科学读物时,要注意抓重点

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

"The big foreign policy issues appear to be Britain's relationship with Europe and the euro, Britain's relationship with the United States, and also questions of the future of Britain's nuclear deterrent."

VOA: standard.2010.04.22

But mainly we're looking for big picture issues.

而是抓住重点

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

"And if we refuse to deal with these issues today, then I guarantee you that they will be an albatross around our efforts [a big obstacle to combat terrorism in the future. The president spoke in the National Archives, which houses the nation's founding documents.

VOA: standard.2009.05.21