It has several meanings. One meaning is that a person who never settles down in one place will not be successful.

VOA: special.2009.06.21

"It never will be." Hen-Tov says Iranian leaders are perplexed - even envious - that a country that was half as rich as Iran was years 30 ago, when the Islamic Revolution took place, is today twice as wealthy as Iran.

VOA: standard.2010.07.26