"Because if you are talking about a teaching force of over 35,000 and you are saying 40 percent of those ones are untrained and unqualified, then it is a big issue."

VOA: standard.2010.02.25

But whenever we've had a reform era there's been a big issue, or two or three or four.

但每当我们有一个改革的时代,都会存在一个,两个,三个或者四个大问题

耶鲁公开课 - 美国内战与重建课程节选

That's a big issue. You can fix one thing, you break something else.

你可以解决一个问题，但你破坏了其它的程序。

麻省理工公开课 - 计算机科学及编程导论课程节选

Health care is a big issue for AARP members.

VOA: standard.2009.07.28

There's never been a successful third-party political culture take hold in this country without one really big issue to drive it.

美国就从没有过,第三政党真正成功执政的时候,因为缺乏一个真正重大的议题来支持它

耶鲁公开课 - 美国内战与重建课程节选

"Absolutely I think that under different circumstances they could have turned it into a big issue in their relationship, and we could have seen mutual accusation and a lot of hysteria on both sides."

VOA: standard.2010.07.09

The lack of housing is also a big issue,partly because of the years of conflict, which have not given us a clear idea of how many homes have actually been destroyed in Afghanistan or badly damaged.

VOA: standard.2009.09.13

"Obviously there is a bit of a spread between those two figures and it suggests the possibility of some political problems for the president if he should not take the military recommendation and that difference gets to be a big issue,".

VOA: standard.2009.10.09

But for people who have a difficult time controlling their movements, this little navigational issue can be a really big problem.

VOA: special.2011.04.18

"That's really the biggest issue. When there is really a big sudden fire, the time to evacuate is extremely limited and extremely dangerous.

VOA: standard.2009.06.24

"You want to hold a review and you want to exclude the one big issue which should be right at the heart of that review."

VOA: standard.2010.04.30