That ligand was one for which the cell had a receptor that further encouraged it to produce more of the ligand.

对于带有对应受体的细胞来说,这种配体能够刺激细胞产生更多的配体

耶鲁公开课 - 生物医学工程探索课程节选

This is called a dative bond.

这种化学键称为配位键。

麻省理工公开课 - 固态化学导论课程节选

The signal comes in the form of molecules which we're going to call throughout the lecture here 'ligands'.

信号通常以分子的形式来传递,在这门课里我们把这种分子叫做配体

耶鲁公开课 - 生物医学工程探索课程节选

In the case of a ligand-receptor, a chemical signal in the form of a concentration of ligand gets converted into a biochemical signal.

在配体-受体系统中,配体浓度这种化学信号,转化为生化信号

耶鲁公开课 - 生物医学工程探索课程节选

For example, what if I activated this cell by encouraging it to produce this particular ligand?

如果促使细胞产生这种特定的配体,以此来激活细胞 会出现什么结果

耶鲁公开课 - 生物医学工程探索课程节选

So, they bind to the receptor - they occupy the receptor so now the natural ligand can't enter it but they don't create the same sequence of biochemical events.

因此,它们与受体结合,它们占据了受体,这样配体就进不来了,但这种结合无法诱发,真正的配体所能诱发的生化反应

耶鲁公开课 - 生物医学工程探索课程节选

So, these are receptors, for example, that bind the ligand and then liberate an enzyme which promotes some sort of reaction inside the cell, often it's kinases but doesn't have to be.

例如,这里是受体,与配体相结合,激活一种酶,这种酶能够催化细胞内的某些反应,这些酶通常都是激酶,但不全是

耶鲁公开课 - 生物医学工程探索课程节选

We're going to talk about this kind of non-covalent interaction more when we talk about the immune system, because one example of ligand and receptors that's important in the immune system are antigens - foreign molecules, and antibodies - molecules that we produce.

当我们讲到免疫系统的时候,会更详细地谈到这种非共价化合反应,因为在免疫系统中,一个重要的配体受体结合反应,就是抗原,即外源分子,与抗体,这个人体自身产生的分子结合

耶鲁公开课 - 生物医学工程探索课程节选

It gets produced in response to a signal so there's a binding of a ligand to a receptor, the enzyme that does this conversion is activated and more cycle AMP is released.

这类分子的产生是对信号做出的一种反应,当配体和受体结合时,催化这种转化过程的酶被激活,更多的cAMP释放出来

耶鲁公开课 - 生物医学工程探索课程节选