• They're everywhere in cells throughout your body and they are responsible for lots of the biochemistry of cell/cell interaction and signaling.

    它们在身体各处的细胞中都有,并负责很多细胞间的相互作用,及信号转导的生化过程

    耶鲁公开课 - 生物医学工程探索课程节选

  • Part of the complexity of the nervous system is the complexity of this interconnection of cells.

    神经系统的复杂性部分地,体现在神经细胞间相互连接的复杂性

    耶鲁公开课 - 生物医学工程探索课程节选

  • Cells of the epithelium are actually "welded" to one another through these junctions called tight junctions.

    上皮细胞通过称为紧密连接的胞连接,"焊接"在一起

    耶鲁公开课 - 生物医学工程探索课程节选

  • It does that through a complex set of sort of cellular interactions, and it turns out also gene rearrangements if you go further to study that.

    而这此过程中,发生了一系列复杂的细胞间的相互作用,也会涉及到基因重排,如果你们深入学习的话就会学到

    耶鲁公开课 - 生物医学工程探索课程节选

  • Because of that, if I eat something that's rich in glucose, so it has lots of sugar molecules, the sugar molecules can't pass between the cells.

    因此,如果我吃了富含葡萄糖的食物,尽管其含有很多的糖分子,但糖分子不能从细胞间通过

    耶鲁公开课 - 生物医学工程探索课程节选

  • What are the sort of basic principles that lead to these differences between cells?

    是怎样的基本原理,导致了细胞间的差异呢

    耶鲁公开课 - 生物医学工程探索课程节选

  • What's different from an immature cell and a mature cell?

    不成熟细胞和成熟细胞间的差异是什么

    耶鲁公开课 - 生物医学工程探索课程节选

  • The way that they communicate with each other is by physically touching each other, and the way that they connect across distances is by having these process that extend from one place to another.

    它们通过物理接触,来交换信息,神经之所以能跨距离传递信息,就是靠细胞间互相延伸的突起

    耶鲁公开课 - 生物医学工程探索课程节选

  • So one way that neurons, in particular, are able to communicate with other cells in the nervous system, share information, integrate information, decide what to do next is that they are physically connected to other different cells.

    所以神经细胞之所以能够,与神经系统中其他细胞通讯,分享信息,整合信息,从而决定下一步该做什么,是由于不同细胞间,是彼此连接在一起的

    耶鲁公开课 - 生物医学工程探索课程节选

  • We're going to talk in some detail, not a very high level of detail, but in some detail about how this communication takes place between cells and how the information is passed down one of these cells today.

    我们还要讨论些细节问题,但不是太深,今天只讲细胞间通讯的发生原理,和信息怎样从一个细胞传递到另一个细胞

    耶鲁公开课 - 生物医学工程探索课程节选

  • These junctions, these red dots here are actually made up of proteins, some are synthesized by one cell, some are synthesized by each other, and they lock together to form a very tight barrier, to form a tight junction between the two cells.

    这些红点表示细胞连接,实际上是由蛋白质构成的,有些是由一个细胞单独生成的,有些是由两个细胞共同生成,使这两个细胞紧锁在一起形成紧密的屏障,并在两细胞间形成紧密连接

    耶鲁公开课 - 生物医学工程探索课程节选

  • One is that there's a physical space in between the two cells, so the axon of what's called the pre-synaptic neuron, or the neuron that's bringing a signal into the synapse, the axon terminal is physically separated from the dendrite of the next cell.

    一是两个细胞间有一定的物理空,所谓的突触前神经元,也就是将信号传递到突触的神经元的,轴突的末梢,同下一个细胞的树突被物理性分离开

    耶鲁公开课 - 生物医学工程探索课程节选

  • Well, it's true that it's not stuck to plastic but it is stuck to other materials The other materials that it's stuck to include other cells that surround it and this complex matrix which surrounds all of the cells in our body called extracellular matrix and I'll get to that in just a few moments.

    体内的细胞不会贴在塑料片上,但是它们会和别的材料黏联在一起,这些材料包括,细胞和周围细胞间的黏联,细胞细胞外基质的黏联,我们身体中包围在细胞周围的物质,称为细胞外基质,后面我会详细讲到

    耶鲁公开课 - 生物医学工程探索课程节选

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