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This is a way for the immune system to recognize things that are going wrong inside the cell protected from antibodies.
这是免疫系统识别,抗体不能识别的细胞内病变的方法
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They're ready to rapidly differentiate into antibody producing cells and they're waiting for that second signal to come.
并可以迅速分化为,抗体分泌细胞,记忆细胞在等待第二次信号的到来
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Because bacteria are outside of cells and when antibodies bind to them they can neutralize them.
因为细菌生存在细胞外,抗体结合细菌并中和掉它们
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Now, why do you need a cell mediated immune response if you have an antibody response?
为什么你还要有细胞免疫反应呢,你已经有抗体应答了啊
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They can't always neutralize viruses because the viruses are predominantly inside cells.
抗体不是总能中和病毒,因为病毒主要在细胞中
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Antibodies are outside of cells circulating in your extracellular fluid.
抗体在细胞外的 细胞外液中循环
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But in any event, the vaccine is intended to stimulate the immune system to produce an effector response— either antibodies or specific cells— that can combat spread of the microorganism through your body.
但无论如何,疫苗是通过,刺激免疫系统来使身体产生应答,无论是抗体还是特定的细胞,都可以阻止微生物在体内扩散
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So, these memory cells are a way that your immune system keeps track of antigens that it's been exposed to for even if maybe the plasma cells that were producing antibody in response to the initial exposure have died and disappeared.
所以,这些记忆细胞,是人体免疫系统记忆抗原的一种方法,即使由浆细胞产生的抗体,在初次免疫应答中全部被消灭,记忆细胞仍然能迅速分化为抗体分泌细胞
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How is your immune system going to recognize that this virus is there causing bad results if it's living inside of a cell and doing all its business inside a cell where antibodies can't get to it?
你的免疫系统怎样才能识别,作恶多端的病毒呢,如果它隐藏在细胞中进行繁殖,而抗体又无法进入细胞,那该怎么办
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Usually the cellular means that they get rid of is that instead of an antibody being produced, you activate a population of cells that will specifically go and hunt down the foreign antigen, or more commonly, cells that contain the foreign antigen.
通常细胞免疫意味着,不用生成抗体就能清除抗原,你激活了一个细胞类群,这一类群能够,并杀伤外源抗原,或者更常见的是,杀伤含有外源抗原的细胞
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The other part of the adaptive immune system is the cell mediated immune system and this is an immune where that doesn't involve antibodies but involves cells that are activated in response to a foreign antigen and that utilize cellular means to get rid of it.
获得性免疫系统还包括,细胞免疫,这一免疫反应不包含抗体,但包含可以被激活来应答,并清除外源抗原的免疫细胞
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They both proliferate, increase in number, and they differentiate; they differentiate from immature B-cells into antibody producing cells.
淋巴细胞将迅速增殖,数量大幅提高,同时发生分化,幼B淋巴细胞分化,形成能够分泌抗体的细胞
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Helper cells don't become cytotoxic cells but they help B cells become antigen producing - antibody producing cells.
附助细胞不会成为细胞毒细胞,它们帮助B细胞成为抗体分泌细胞
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The humoral immune response involves antibody production and antibodies are made by a subset of cells called B-cells.
体液免疫反应中包括抗体的产生过程,抗体是由一类称为B细胞的细胞亚族产生
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They know that these cells are harboring the virus because those cells have foreign antigens on their MHC1.
它们能知道哪些细胞窝藏病毒,因为这些细胞的MHC1上有外源抗体
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The antibody that they stimulate is antibody that's specific to this antigen that was presented earlier.
这些由辅助性T细胞,刺激增殖产生的抗体是,对应之前出现的抗原而产生的
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So not all of the B-cells that are stimulated become plasma cells or antibody secreting cells.
所以,并不是所有的B淋巴细胞,被刺激分化成为,浆细胞或是抗体分泌细胞
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Now, for antibody production it is still a T-cell that recognizes the antigen presenting cell.
现在,抗体的产生,仍是源于T淋巴细胞识别出抗原呈递细胞
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They come from B-cells, they come from B-cells that are activated with a specific antigen.
抗体来自于B细胞,它们来自于被特别的抗原所激活的B细胞
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The antibodies that are produced from these B-cells are also specific for the antigen.
产生自B细胞的抗体,对抗原来说是特异性的
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That's shown here, a B-cell gets stimulated, matures into an antibody producing factory.
这里展示的是,当一个B细胞被激活,分化成熟为一个生成抗体的工厂
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In the case of the helper cells they stimulate a specific population of B-cells to mature into antibody producing cells, and that antibody is generated against the antigen that stimulated it.
以辅助性T细胞为例,辅助性T细胞刺激特定的B细胞,使这些细胞成长为抗体分泌细胞,抗体分泌细胞产生大量的抗体,以消灭大量增殖的抗原
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Now, these Th-cells, helper T-cells, go on to stimulate B-cells, and it's these B-cells that become the mature antibody producing cells that make quantities of antibody that fill up in your body.
这些辅助性T细胞,进一步刺激B淋巴细胞,从而使这些B淋巴细胞,逐渐发育成成熟的抗体生成细胞,可在体内产生大量抗体
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So, either stimulates the production of-- and differentiation of B-cells, to produce a specific antibody that can neutralize the virus, or stimulates the production of cytotoxic T-cells that can kill infected cells within your body.
所以,疫苗的刺激要么能够,促进B淋巴细胞产生和分化,以生成特定的抗体来杀灭病毒,要么刺激T细胞释放细胞毒素,杀死身体里被感染的细胞
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Cells share signals with each other, and that leads to activation of a specific cell population if we're thinking about a vaccine that produces antibodies, that leads to activation of B-cells, immature B-cells, which do two things.
细胞与细胞之间存在信号传递,而这将激活特定的细胞群体,如果是一些能够产生抗体的疫苗,抗体将会激活B淋巴细胞,幼B淋巴细胞,使其发生两种变化
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