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If I could find the unique set of proteins that correspond to those genes I could define chemically what the cell is.
而我又能找到和这些基因对应的,这种独特的蛋白,我就能通过化学手段确认这是哪种细胞
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When they do find the cell they're capable of interacting with the receptor forming some kind of chemical interaction with the receptor.
但当它们遇到细胞时,就能够与受体相互作用,与受体发生化学反应
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If you could look at these cells you could find differences between them, there are chemical differences in the content of each of these cells.
如果观察这些细胞,你就能发现这些差异,每个细胞内容物的化学成分,都会有一些不同
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Now, the differences here may be subtle in terms of chemical composition or if you put these cells under a microscope and looked at their analysis.
干细胞与祖细胞化学成分的区别,还非常微小,除非你把细胞放在显微镜下,或者看细胞分析报告
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The way that the cell experience it is through some sort of biochemical changes.
细胞发生某种生物化学变化,以完成这个过程
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By cell/cell contact, I mean that there's a receptor in one cell that makes some kind of a chemical interaction with a receptor in another cell.
通过细胞之间的接触,我的意思是在一种细胞上的受体,能与另一细胞上的受体发生某种化学反应
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When it does it makes biochemical changes inside the cells and one of the things it does is increase glucose uptake into certain kinds of cells, particularly fat cells and muscle cells.
这导致细胞内部发生生物化学变化,其中的一个变化是,某些细胞开始增加对糖分的摄取,尤其是脂肪细胞和肌细胞
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In the time it takes for one cell division to occur, it could be that this cell entraps a different chemical composition of the cytoplasm then this entraps, and that's a well known concept.
当一个细胞分裂发生期间,很可能这个细胞截留了一种不同的,细胞质化学组分,这种非对称分裂是一个广为人知的概念
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This is a mechanism by which an electrical signal comes here, it gets translated into a chemical signal, the chemical diffuses across the gap and reinitiates a - an electrical signal in the next cell and that's one way that it happens.
这就是电信号产生的机理,电信号翻译成化学信号,化学物质扩散过突触间隙,重新激起下个细胞中的电信号,这是一种方式
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If that protein is an enzyme then you've and you've switched it from an 'off' position where it's not catalyzing a reaction to an 'on' position where it is, you've changed the biochemical state of the cell, you've changed the chemical reactions that can occur within the cell, and you've changed its behavior.
如果这种蛋白是一种酶的话,你就能够将酶从无催化作用的静息态,激活至能催化反应的激活态,你改变了细胞的生化状态,也改变了细胞内发生的化学反应,改变了细胞的行为
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So the access that a cell has to certain kinds of genes, or chemical modifications of DNA, not chemical modifications that change the base pairs, that would be a mutation.
因此细胞变化的途径应该是对某些基因,或者DNA进行化学修饰,不是更改碱基对,更改碱基对就是突变了
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So my goal today is to talk about sort of the basics of the molecules, their chemistry, the function of DNA in cells, sort of basic - the basic side of that.
所以我今天的任务是告诉你们,DNA分子的各种基团,它们的化学结构,细胞内DNA分子的功能
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