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This is a way for the immune system to recognize things that are going wrong inside the cell protected from antibodies.
这是免疫系统识别,抗体不能识别的细胞内病变的方法
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That's what's illustrated here with the end result being that there's some change in the life of the cell.
这里显示的是,在信号放大传递后,细胞内发生的变化
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So essentially, they regulate this action potential, and they do so by helping to establish and then control the voltage gradient within the cells.
总之本质上，它们负责调节动作电位,它们做到这一点通过协助制造,并控制细胞内的电位梯度。
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It has the capability of becoming any kind of cell within the body, in fact, that's what it does.
它能成为身体内任何种类的细胞,事实上,这也就是它的功能
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This is a signal - this passing of phosphorous - is a signal that's used very frequently in intracellular communication.
这是一种信号,一种通过磷酸来传递的信号,这种信号在细胞内通讯时经常被用到
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So, this pathway might not be the only one that's being activated inside the cell at any given time.
因此,任一时刻细胞内,激活的信号通路不只是一条
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So, they don't start killing all the cells in your respiratory system; they only kill the cells that are harboring the virus.
所以它们不会杀死所有呼吸系统内的细胞,只杀死那些被病毒感染的细胞
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Many steroid hormones act because they bind to cellulars - to receptors that are deep within the cell, often inside the nucleus.
许多类固醇激素能够起效是因为,其与存在于细胞内部的受体相结合,这类受体通常在细胞核内
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The cells of this cluster inside next to the fluid filled cavity is a region of the blastocyst called the inner cell mass.
而这簇细胞的内侧,毗邻于充满液体的空腔的一侧,这些细胞在囊胚中称为内群细胞
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They're red because they contain a special protein called hemoglobin which is very concentrated inside the cell.
红细胞的红色源于,其内部一种叫做血红蛋白的特殊蛋白质,血红蛋白在细胞内的浓度很高
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It's this - its cells in this region here, this inner cell mass that that's the source of embryonic stem cells, cells from inner cell mass here.
就是这个,在这片区域的胚胎细胞,即内细胞群,而胚胎干细胞的来源所在,就是源自这里的内细胞群
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In general, inside of a cell molecules move by a process called diffusion.
总的来说,细胞内的分子通过扩散作用来移动
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That virus is reproducing inside cells of your respiratory tract.
病毒在你的呼吸道细胞内繁殖
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Further down the line, for example, in the blastocyst I talked about before, we could obtain cells from this inner cell mass or this cluster of cells that becomes the embryo.
沿着这条线看,举个例子,就是我之前提到过的囊胚,我们可以取一些内细胞群的细胞,这种能成为胚胎的细胞群
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The notion is, if there's something foreign that's being produced inside this cell, then that cell must have been corrupted in some way and it has to be gotten rid of.
免疫反应的规矩是这样的,如果某些外源物在你细胞内产生,那说明这个细胞的某些地方,已经被损害了所以必须被清除掉
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So, these are receptors, for example, that bind the ligand and then liberate an enzyme which promotes some sort of reaction inside the cell, often it's kinases but doesn't have to be.
例如,这里是受体,与配体相结合,激活一种酶,这种酶能够催化细胞内的某些反应,这些酶通常都是激酶,但不全是
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A progenitor cell, the definition, it just means it can generate the cells that are typical of that tissue or that organ, so it's capable of becoming these mature classes of cells.
祖细胞的定义就是,它能产生那个器官或者组织内的,所有的典型细胞,所以它可以成为那一类的成熟细胞
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One way that you could switch this on and off inside the cell is by taking off this phosphorous, proteins enzymes that do this opposite reaction, the opposite to kinases are called phosphokinases.
一种方法是通过去除磷酸基团,来改变细胞内蛋白的状态,催化添加磷酸基团,此逆反应的蛋白酶,能够催化逆反应的激酶叫做磷酸激酶
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If that protein is an enzyme then you've and you've switched it from an 'off' position where it's not catalyzing a reaction to an 'on' position where it is, you've changed the biochemical state of the cell, you've changed the chemical reactions that can occur within the cell, and you've changed its behavior.
如果这种蛋白是一种酶的话,你就能够将酶从无催化作用的静息态,激活至能催化反应的激活态,你改变了细胞的生化状态,也改变了细胞内发生的化学反应,改变了细胞的行为
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I did want to say a little bit more about kinases because they're so important in intracellular communication and kinases take advantage of the fact that proteins can often exist in more than one state, and that's what makes them useful molecules inside cells.
关于激酶我想再多讲一点,因为它们对细胞内通讯十分重要,因为激酶的优越之处在于,这种蛋白通常不只有一种状态,这也令它们在细胞中的用处极大
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These molecules of DNA, very long molecules of DNA, are condensed and packaged within the nucleus of every cell in your body.
这些DNA分子是非常长的,它们通过折叠等方式压缩形成染色体后,被装配在你身体内的每一个细胞内
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They enter the cell after recognizing, they fall apart inside the cell, they reproduce their DNA, or their genetic material using host mechanisms.
在识别细胞后侵入之,它们在细胞内解体,复制自身的DNA,利用宿主的遗传来机制复制自己的DNA
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That is, that the information needed to operate a cell is stored in its DNA.
所以说细胞工作所需的的全部信息,都被存储在DNA内
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The G-protein then goes on to create some other biochemical changes inside the cell.
然后G蛋白在细胞内,诱发其它的一些生化反应
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In this same way, this process of transcription which is occurring in cells throughout body all the time is made possible by a protein called RNA polymerase.
NA的合成也很类似,身体内每个细胞内,转录过程的进行都是在一种称作,RNA聚合酶的蛋白质催化下进行的
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It's the way that DNA exists inside the cells of your body.
你身上细胞内的DNA就是这样子的
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Well, the way that your immune system recognizes it is that all the cells of our body express a molecule on their surface, a membrane protein called the MHC1 complex.
而免疫系统识别的方法是,身体内所有细胞在其表面表达一种分子,一种叫做MHC1复合体的膜蛋白
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When a certain enzyme is activated inside cells, ATP gets converted into a molecule called cyclic AMP, and cyclic AMP is an example of one of these molecules called second messengers.
细胞内的某种酶被激活后,ATP就能转化为一种叫cAMP的分子,cAMP是一种第二信使分子的范例
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So my goal today is to talk about sort of the basics of the molecules, their chemistry, the function of DNA in cells, sort of basic - the basic side of that.
所以我今天的任务是告诉你们,DNA分子的各种基团,它们的化学结构,细胞内DNA分子的功能
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The other thing that it does is that when a virus is inside these cells making its proteins, some of those proteins get processed or digested into small fragments that are themselves antigens.
HC的另一项作用是,当病毒在细胞内表达蛋白时,一些蛋白被加工,或者,分解成小片段而成为抗原
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