It's a single gene defect and we know exactly where the genetic defect is in sickle cell.

是一种单基因缺陷,而且我们准确地知道,镰状红细胞贫血的基因缺陷在哪里

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It can be used given to people to who have certain kinds of anemia to stimulate blood cell production in a specific kind of way.

它能够用于那些,罹患某种贫血的人群,来以特定的方式刺激红细胞生成

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It's on the gene for hemoglobin and the hemoglobin that you produce if you have sickle cell anemia is not quite right because there's one base difference.

这个缺陷基因和血红蛋白有关,如果你有镰状红细胞贫血症,那你所产生的血红蛋白就不太正常,因为这里有一个碱基不同

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Sickle cell anemia is a disease that affects a subset of the population.

镰状红细胞贫血症,是一种作用于特定人群的疾病

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Here's the difference between normal hemoglobin and sickle hemoglobin, I can make - I can see a chemical difference, I can exploit it, how can I find it?

正常血红蛋白和镰状红细胞贫血的,血红蛋白有不同之处,我能够--我能看出有化学差异,我能去探寻差异,那么我怎么找到它呢

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This particular example involves the gene for sickle cell anemia.

本例子中就包括镰状红细胞贫血症的基因

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If this was a sickle patient, so they had this gene instead it wouldn't get cut and when I went to look for that presence of that gene on this gel, it would appear as one large segment instead of a large one and a smaller one.

而如果是个镰状红细胞贫血的病人,他们的基因是不会被限制酶切割的,因此他们基因的凝胶电泳结果就不会呈现,一大一小的结果,而只有一个大的片段

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Erythropoietin, commonly called Epo and its function is to treat anemia because it stimulates blood cell production.

促红细胞素生成素,通常简称为EPO,它的作用是刺激红细胞生成,从而能够治疗贫血

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