They bind sometimes better than the natural ligand does, but they don't create the right biological reaction.

结合的比天然配体和受体的的结合更紧密,但不能产生相同的生物效应

耶鲁公开课 - 生物医学工程探索课程节选

I think that a lot of the countries in Europe want to have a closer political and economic integration.

我认为，很多欧洲国家想相互之间有一个更紧密的政治、经济上的结合。

欧洲中的英国 - SpeakingMax英语口语达人

The other thing that I want to do today is try to tie this discussion on vaccines a little bit more closely with what we talked about last week, in terms of what happens inside your body when you receive a vaccine or when you're exposed to an antigen, and how the immune system actually responds to that.

还有就是,我希望可以,把今天关于疫苗的讨论,与我们上周讲过的内容,结合得更紧密一些,当接种疫苗,或者是接触抗原时,人体将会发生怎样的变化,以及免疫系统对疫苗产生何种应答

耶鲁公开课 - 生物医学工程探索课程节选

Because they're much more integrated with the city.

因为这些学校和城市的结合更加紧密。

耶鲁奖学金获得者 - SpeakingMax英语口语达人

Now DNA is a double helix and I've only shown you one part of the helix, right? I've shown you one upright strut and a base hanging off of it, but it forms a double helix because complementary strands of DNA strongly associate with one another and that's a very stable structure.

NA是双螺旋,我只是给你们讲了螺旋的一边,我给你们演示,一条链的支柱及碱基团,但其能构成双螺旋,是因为DNA是完全互补的两条链,彼此之间结合紧密,结构异常稳定

耶鲁公开课 - 生物医学工程探索课程节选