• This is a way for the immune system to recognize things that are going wrong inside the cell protected from antibodies.

    这是免疫系统识别,抗体不能识别的细胞内病变的方法

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  • People have tried to produce viruses that are different, adenoviruses for example, that your immune system can't recognize.

    人们尝试制造一些不同的病毒,就拿腺病毒来说,让免疫系统无法识别

    耶鲁公开课 - 生物医学工程探索课程节选

  • You're taking advantage of a promoter system, or a gene activation system, that this species knows about because adult animals can make milk.

    我们之所以能利用这个启动子系统,或者称之为可以被这一物种识别的,基因活化系统,是因为成年动物可以泌乳

    耶鲁公开课 - 生物医学工程探索课程节选

  • What happens when that recognition takes place is that your immune system gets activated, and the activation that happens usually involves two things.

    识别进行时会发生什么呢,那时免疫系统会激活,免疫系统的激活通常包含两个过程

    耶鲁公开课 - 生物医学工程探索课程节选

  • Other cells in the immune system recognizing that this is a foreign molecule, but is being presented in the context of a 'self' cell.

    免疫系统中的其他一些细胞,识别到它是非己物质,但它已经被识别为己方细胞

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  • Then, your muscle cells would start producing Hepatitis B surface antigen and your immune system recognizing that's a foreign protein would start responding to it.

    于是,肌肉细胞将会,开始制造乙肝表面抗原,然后免疫系统就会识别出,那是外来蛋白质并且产生免疫应答

    耶鲁公开课 - 生物医学工程探索课程节选

  • A problem with adenoviruses is that your immune system recognizes them, and if your immune system recognizes the virus then it can attack the virus and eliminate it from the body.

    关于腺病毒有个问题,免疫系统识别腺病毒,如果免疫系统识别了这些病毒,就会进而攻击并从体内清除病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • It can separate between what's part of yourself and what's foreign, and it does that by presenting, by recognizing antigens that are presented in the context of the major histocompatibility complex, MHC.

    免疫系统可以识别出哪些是属于你的,哪些是外来的,它通过呈递和识别抗原达到目的,而抗原是存在于,主要组织相容性复合体中的

    耶鲁公开课 - 生物医学工程探索课程节选

  • How is your immune system going to recognize that this virus is there causing bad results if it's living inside of a cell and doing all its business inside a cell where antibodies can't get to it?

    你的免疫系统怎样才能识别,作恶多端的病毒呢,如果它隐藏在细胞中进行繁殖,而抗体又无法进入细胞,那该怎么办

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  • If the immune system recognizes only small pieces of the virus and mounts an immune response to that, how about if I just take these pieces of a virus like some structural subunit, some piece of protein and use that as a vaccine?

    如果免疫系统识别出病毒的一小段,就可以诱发起免疫应答,那么如果我仅用一小部分病毒,比如一些结构性亚基 一些蛋白质的片段,来作为疫苗的话,会如何呢

    耶鲁公开课 - 生物医学工程探索课程节选

  • And so we talked very briefly last time about this business of antigen presentation, how your immune system-- one of the things that it does especially well, is recognize what's part of you and what's not part of you.

    上次我们简单的提到过,有关抗原呈递的一些知识,你的免疫系统如何,这也是免疫系统尤其擅长的一点,就是识别哪些部分属于你,哪些不属于

    耶鲁公开课 - 生物医学工程探索课程节选

  • Well, the way that your immune system recognizes it is that all the cells of our body express a molecule on their surface, a membrane protein called the MHC1 complex.

    而免疫系统识别的方法是,身体内所有细胞在其表面表达一种分子,一种叫做MHC1复合体的膜蛋白

    耶鲁公开课 - 生物医学工程探索课程节选

  • If you take an organ from one person and put it in another, if their MHC molecules don't match then the immune system recognizes the immune system of the host recognizes 'this is not the right MHC for me' and the immune tries to destroy those cells.

    如果将器官从一个人移植到另一个人,免疫系统识别出MHC分子并不匹配,宿主的免疫系统就会说,这不是我的MHC,免疫系统就会试着摧毁移植器官的细胞

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