Proteins are only susceptible to phosphorylation if they have certain kinds of amino acid sequences.

只有含这些氨基酸的蛋白质,才能够被磷酸化

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One of the amino acids that can be phosphorylated is tyrosine, for example.

例如,一种能够被磷酸化的氨基酸,叫做酪氨酸

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Often the state of a protein depends on whether it's phosphorylated or not.

蛋白的状态通常取决于,它们是否被磷酸化

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Now, being phosphorylated means that a phosphate group has been added to the protein, and phosphate groups can only be added to certain amino acids along a protein.

磷酸化的意思是,蛋白上连接了一个磷酸基团,这个磷酸基团只能连在,蛋白中某些特定的氨基酸上

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It generates a kinase activity which leads to phosphorylation of the protein.

它产生了一种激酶活性,导致了受体蛋白的磷酸化

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So, a protein that has tyrosine and it has tyrosine in a position such that it's on the outside of the protein and accessible to chemical reaction can be phosphorylated.

所以,一种蛋白质中含有酪氨酸,并且该酪氨酸位于,像蛋白质的外侧这样的位置,这样才能够发生磷酸化反应

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In this case, a receptor tyrosine kinase is a receptor molecule that binds a ligand at its surface outside the cell and initiates this enzyme activity - this kinase activity - and causes phosphorylation of another molecule.

在这个例子中,酪氨酸激酶受体可以,在细胞表面区域与配体结合,从而激发出,激酶的活性,使其能够磷酸化另一类分子

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