When transcription happens and it turns out that there's a whole biology associated with this, including molecules that are floating around inside your cells called transcription factors, and their job-- they are molecules that are about particular genes and what some of the sequences and are able to turn on those genes inside cells, to make them transcribe.

研究证明,当细胞转录时,还有与之相关的一整套生物机制在运作,包括一种在你细胞中飘浮着的,称为转录因子的分子,它们的工作就是,它们知道该转录哪一段基因,该转录哪一段序列,然后把这些细胞中的基因激活,进行转录

耶鲁公开课 - 生物医学工程探索课程节选

The end result is you can design now very specific double stranded RNA sequences, that when delivered into cells again will activate this process of natural degradation of an existing messenger RNA.

最终的结果是,你现在能够设计针对性很强的,双链RNA序列,当这段序列被转入细胞后会激活,对已有信使RNA进行降解的过程

耶鲁公开课 - 生物医学工程探索课程节选