Now, why do you need a cell mediated immune response if you have an antibody response?

为什么你还要有细胞免疫反应呢,你已经有抗体应答了啊

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Basically, injecting it into some test subjects, making sure that they didn't get diseased from it and looking at antibody responses to see if it worked and it did.

他们把疫苗接种到测试对象体内,确定接种者不会感染疾病,同时观察抗体的应答反应,了解疫苗是否有效

耶鲁公开课 - 生物医学工程探索课程节选

But in any event, the vaccine is intended to stimulate the immune system to produce an effector response— either antibodies or specific cells— that can combat spread of the microorganism through your body.

但无论如何,疫苗是通过,刺激免疫系统来使身体产生应答,无论是抗体还是特定的细胞,都可以阻止微生物在体内扩散

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If we just thought about that second part of it, just the antibody generation, or the humoral what we called last time--last week, the humoral immune response, the immune response associated with humoral immune response of antibodies in the blood and in other fluids.

当我们仅考虑上述过程的第二步,也就是产生抗体的部分,或是我们上周学习的,体液免疫应答,这种免疫应答与,血液中以及其他体液中的抗体有关

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So, these memory cells are a way that your immune system keeps track of antigens that it's been exposed to for even if maybe the plasma cells that were producing antibody in response to the initial exposure have died and disappeared.

所以,这些记忆细胞,是人体免疫系统记忆抗原的一种方法,即使由浆细胞产生的抗体,在初次免疫应答中全部被消灭,记忆细胞仍然能迅速分化为抗体分泌细胞

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The other part of the adaptive immune system is the cell mediated immune system and this is an immune where that doesn't involve antibodies but involves cells that are activated in response to a foreign antigen and that utilize cellular means to get rid of it.

获得性免疫系统还包括,细胞免疫,这一免疫反应不包含抗体,但包含可以被激活来应答,并清除外源抗原的免疫细胞

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Now, if I was a person that was designing a vaccine and I noticed that this was the response that it got, that antibodies were produced, they reached some intermediate level, they started to fall, I would say, "Well I haven't stimulated the immune system enough, let me re-boost, let me give another dose of antigen."

现在,如果我正在研究一种疫苗,我注意到机体会对这种疫苗产生应答,也就是会产生抗体,当抗体浓度达到中等水平后,就开始下降,就可以说,疫苗对免疫系统刺激还不足,我需要提高抗原浓度,让我再把剂量再加大一倍

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If you looked later, as the antibody production response matures, some IgG is produced so that in the late period after initial priming you'd have a mixture of IgM and IgG in the blood.

如果你稍后再观察,等到产生抗体的应答趋于成熟后,就会产生一些IgG抗体,在初次免疫的最终阶段,你的血液中有IgM,和IgG两种抗体

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