When, if ever, is suicide an appropriate, ? rational or moral response to one's situation?

什么时候，如果有的话，自杀是合适的，合理的或道德的回应呢？

耶鲁公开课 - 死亡课程节选

I'm not free to take my own life or to sell my self into slavery or to give to somebody else arbitrary absolute power over me.

不能随意自杀,或出售自己成为奴隶,或给别人绝对权力，任意主宰我。

耶鲁公开课 - 公正课程节选