This concept of introducing foreign genes, genes that are made of recombinant DNA into animals using this kind of technique is widely used in biomedical research.

这种通过基因重组,来向动物体内导入外源基因的方法,广泛应用于,各种生物医药的研究中

耶鲁公开课 - 生物医学工程探索课程节选

One way that that's done is by introducing genes into cancer cells, genes that aren't normally expressed in any mammalian cell, but that will cause the cancer cell to die.

已经成功应用的一种方法是,将基因导入癌细胞,而这种基因通常不在哺乳动物细胞中表达,但是可以导致癌细胞的死亡

耶鲁公开课 - 生物医学工程探索课程节选

These are ways to stop a gene from being expressed, and there turns out there's lot of applications in that, lots of diseases result from the unwanted expression of certain kinds of genes and cancer is probably the best example of that, but there are many.

有些方法能够终止基因的表达,而这些方法也经证实有广泛的应用,有很多疾病是源于基因的异常表达,而癌症大概是这种情况最好的例子,但还有很多其他的

耶鲁公开课 - 生物医学工程探索课程节选

Before we talk about how to do it-- and we don't have perfect ways to do it yet but I'll describe some of the ways that are used, I want to talk just briefly on this slide about what the goals for gene therapy might be.

在讲具体怎么做之前--,现在还没有任何一种方法是完美的,但我还是要讲讲一些已经应用的方法,我借助这张幻灯片简要介绍一下,基因治疗的可能目标

耶鲁公开课 - 生物医学工程探索课程节选

I talked about just not using viruses but using plasmid DNA together with lipids and that's another strategy for gene therapy.

这一部分我们不仅讲了病毒的应用,也讲了利用脂质体包裹的质粒DNA,基因治疗还有其它的策略

耶鲁公开课 - 生物医学工程探索课程节选

We'll start with Week 2 talking about Genetic Engineering; what's DNA, how can it be manipulated, how is our ability to manipulate DNA led to things like gene therapy which can now be done in people.

从第二周开始我们会讲基因工程,什么是DNA,怎么样才能操控它们,我们如何操作DNA,并将它应用于人类的基因疗法

耶鲁公开课 - 生物医学工程探索课程节选