• The end result is you can design now very specific double stranded RNA sequences, that when delivered into cells again will activate this process of natural degradation of an existing messenger RNA.

    最终的结果是,你现在能够设计针对性很强的,双链RNA序列,当这段序列被转入细胞后会激活,对已有信使RNA进行降解的过程

    耶鲁公开课 - 生物医学工程探索课程节选

  • Well, what if you knew the sequence for the messenger RNA that made insulin and you designed another single stranded DNA or RNA molecule that was the exact opposite, or the exact compliment, I should say, of that strand?

    那么,如果你知道了,合成胰岛素的mRNA的序列,并设计一段与其序列完全相反的,DNA或者RNA分子,应该说是完全互补的一段分子

    耶鲁公开课 - 生物医学工程探索课程节选

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