Knowing what you know now, any concerns about taking the oral polio vaccine instead of getting the shot?

依据当前结果,你对口服疫苗替代,注射疫苗有何担心吗

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This is the vaccine that you probably took; the vaccine that's still most widely used in the U.S.

你可能也服用过这种疫苗,在美国这种口服疫苗至今

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In the Sabin vaccine, or the oral polio vaccine, now you have a non-virulent virus.

在沙宾疫苗,即口服小儿麻痹症疫苗中,存在非致病性病毒

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In fact, another advantage of the oral vaccine is that you give it to children.

实际上,口服疫苗的另一个优势是,它用来给小孩服用

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Why would you maybe not want to use the oral vaccine?

但什么会让你不愿意使用口服疫苗呢

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An oral polio vaccine was developed by a man named Sabin.

一个名叫萨宾的人研发出了,一种口服小儿麻痹症疫苗

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He produced an oral polio vaccine from an attenuated virus.

他利用减毒病毒制得口服小儿麻痹症疫苗

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If you could take your five year-old or eight year-old in to get a vaccine that was orally administered instead of a shot that's a much easier thing to do.

如果你带着五岁或者八岁的孩子,去口服而不是去注射疫苗,那将会轻松许多

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Plus it makes it, as I talked about last time, much easier to think about distributing the vaccine around the world because shots require skilled medical personnel, whereas, an oral vaccine could be self-administered.

而且,这会使得,就像我上次谈到的,这会使得疫苗更容易在世界范围内分发,因为注射需要专业医疗人员,但是,口服疫苗自己就可以服用

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It turns out that if you give one child in a home the oral vaccine, you often have a protective effect in other children in the home as well because it spreads from one individual to another.

结果显示,如果给一个家庭中的,一个孩子服用了口服疫苗,就等于给家中的其他孩子,同样进行了保护,因为它会在个体之间进行传播

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Particularly, if we took advantage of the fact that this is a virus that's easily transmitted orally and could you make a vaccine that would be effective orally as well, that would be a tremendous advantage, especially in children who don't like to get shots.

尤其是,如果我们可以利用这种病毒,很容易经口传播这一事实,制造出一种,可以通过口服而起到同样效果的疫苗,那么这将是一个巨大的飞跃,特别是对于那些不喜欢打针的孩子

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So, it's more effective because it's a live virus but it's a little bit more concerning because it's a live virus as well, in that you trust that it's attenuated but could it convert back to a virulent form or a form that caused a disease.

因此,口服疫苗更加有效,因为它是活性病毒,但又是因为这一点,人们也存有更多顾虑,当它处于减毒状态时你会信任它,但是它会不会转变回,强毒壮态或者致病状态呢

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