• The end result is you can design now very specific double stranded RNA sequences, that when delivered into cells again will activate this process of natural degradation of an existing messenger RNA.

    最终的结果是,你现在能够设计针对性很强的,链RNA序列,当这序列被转入细胞后会激活,对已有信使RNA进行降解的过程

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now the nice thing about this is that the degradation mechanisms seem to persist for some period of time, beyond the time at which you deliver the double stranded RNA; whereas, obviously, this mechanism here is only going to exist for as long as the anti-sense sequence is present.

    而好消息是降解过程会持续一时间,比你转入链RNA的时间要长,但是,这种机制只会在,有反义链的时候发挥作用

    耶鲁公开课 - 生物医学工程探索课程节选

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