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There's not actually chemical covalent bonds that are formed but it's a non-covalent interaction, usually dominated by hydrogen bonding.
所以配体和受体之间不生成共价键,这是一种非共价化合反应,它们通常以氢键相联
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And from that, then you can look at enthalpies of reaction for countless numbers of reactions, right.
很多很多种化合物,利用这些你就可以研究,不计其数的反应的反应焓。
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And what it's used is to convert one type of group, what's called a carboxylic acid into another type of very reactive intermediate, which is called an acid chloride.
它被用来将一类被称作羧酸的化合物，转化成另外一类活性很高的反应中间体,也就是酰氯。
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Now, usually this is a non-covalent interaction.
这通常是一种非共价化合反应
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Maybe you're not looking at a reaction, but you've got some new compound, and you're looking at it go from liquid to solid or to gas.
也许你研究的不是一个反应,但你得到了一种新的化合物,你看着它从液体变成了固体或气体。
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Well, I need to write the reaction that forms that compound from it's elements, right?
我需要写出从元素单质生成,这种化合物的反应，对吧？
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But in terms of drugs that don't look like maybe this compound was used in the synthesis, many of them might have used thionyl chloride, because it generates such a nice reactive intermediate that you can go on and make a bunch of different compounds from that intermediate.
但是对于药物来说,它们可能跟合成过程中用到的这种化合物并不相像，很多药物的制造过程中都会用到亚硫酰氯，因为它能产生活性如此之高的反应中间体,以至于你可以继续利用反应中间体,来制造一堆不同类型的化合物。
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We can tabulate them. We can know them, and then when we have reactions that inter-convert different compounds, we can calculate the heat of reaction is just the difference between the heat of formation of the reactants, and the heat of formation of the products, right.
种化合物的生成热，可以把它们列成表,可以认知它们，而当我们要处理，在不同化合物间转变的反应时,我们只要计算反应物和,生成物的生成热之间的不同,就能计算出反应热。
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We're going to talk about this kind of non-covalent interaction more when we talk about the immune system, because one example of ligand and receptors that's important in the immune system are antigens - foreign molecules, and antibodies - molecules that we produce.
当我们讲到免疫系统的时候,会更详细地谈到这种非共价化合反应,因为在免疫系统中,一个重要的配体受体结合反应,就是抗原,即外源分子,与抗体,这个人体自身产生的分子结合
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