You feel desperate because you know that if you crash into these five workers, they will all die.

你此时极度绝望,因为你深知,如果电车撞向那五名工人，他们全都会死。

耶鲁公开课 - 公正课程节选

Surrounded--Surrounding--To complete a mechanical metaphor that would have led Descartes to despair-- Thank you, Koleen.

这也是个可以让笛卡尔绝望的,机械性隐喻,谢谢你,柯琳

耶鲁公开课 - 心理学导论课程节选

So don't be--don't despair if you don't initially land on the tonic here.

所以如果你不能一次找到主音也不要，，不必绝望。

耶鲁公开课 - 聆听音乐课程节选