• There's a diverse range of responses that might occur, but that response is initiated by this simple chemical process of a ligand binding to a receptor.

    细胞对外界信号可能会发生不同的反应,但这些反应都源自,配和受结合这个简单的化学过程

    耶鲁公开课 - 生物医学工程探索课程节选

  • Could be done, but easier is to just do the whole thing at constant volume, right, and just run the reaction that way and redo the calculation to be a constant volume rather than constant pressure calorimeter, right.

    可以进行测量,但是如果在积恒定的条件下,做这些会容易得多,还是这样进行反应,但是在等而不是恒压条件下重新计算。

    麻省理工公开课 - 热力学与动力学课程节选

  • So, they bind to the receptor - they occupy the receptor so now the natural ligand can't enter it but they don't create the same sequence of biochemical events.

    因此,它们与受结合,它们占据了受,这样配就进不来了,但这种结合无法诱发,真正的配所能诱发的生化反应

    耶鲁公开课 - 生物医学工程探索课程节选

  • We're going to talk about this kind of non-covalent interaction more when we talk about the immune system, because one example of ligand and receptors that's important in the immune system are antigens - foreign molecules, and antibodies - molecules that we produce.

    当我们讲到免疫系统的时候,会更详细地谈到这种非共价化合反应,因为在免疫系统中,一个重要的配结合反应,就是抗原,即外源分子,与抗,这个人自身产生的分子结合

    耶鲁公开课 - 生物医学工程探索课程节选

  • It gets produced in response to a signal so there's a binding of a ligand to a receptor, the enzyme that does this conversion is activated and more cycle AMP is released.

    这类分子的产生是对信号做出的一种反应,当配和受结合时,催化这种转化过程的酶被激活,更多的cAMP释放出来

    耶鲁公开课 - 生物医学工程探索课程节选

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