To disfigure the mouth -- this is how I would interpret it -- to disfigure the mouth has a primary effect in rendering one at least temporarily speechless.

把嘴巴丑化--这就是我所理解的-,丑化自己的嘴巴使自己暂时不能说话,它是有十分重要影响的。

耶鲁公开课 - 弥尔顿课程节选

And other patients suffer from Lou Gehrig's diseases and so forth are not even able to speak at all, and not able to perhaps blink their eyes to communicate.

其他患有葛雷克氏症的人等等,甚至一点都不能说话，不能通过眨眼的方式与人交流。

斯坦福公开课 - 7个颠覆你思想的演讲课程节选