• Insulin is a naturally occurring hormone, it's a protein hormone that circulates in all of our bodies and regulates glucose metabolism.

    胰岛素是人体自身产生的一种激素,它是一种蛋白质激素,遍布全身,并调节糖代谢

    耶鲁公开课 - 生物医学工程探索课程节选

  • That's one of the beauties of proteins as working molecules is that their structure can be changed by subtle means.

    蛋白质作为一种生物活性分子,其优势之是,能够通过精细的方法改变其结构

    耶鲁公开课 - 生物医学工程探索课程节选

  • For some of you that haven't I'll just say that it's a protein, it's 238 amino acids, which means that it's about 1,000, actually more than 1,000 atoms in size, and this protein is fluorescent.

    对于那些没听说过的人,我要说它是一种蛋白质,它有238个氨基酸,也就意味着它有约1000个,实际上是超过1000个原子,这种蛋白质是有萤光的。

    麻省理工公开课 - 化学原理课程节选

  • They're red because they contain a special protein called hemoglobin which is very concentrated inside the cell.

    红细胞的红色源于,其内部一种叫做血红蛋白的特殊蛋白质,血红蛋白在细胞内的浓度很高

    耶鲁公开课 - 生物医学工程探索课程节选

  • Well, insulin is a protein, it's produced by cells in the pancreas, it circulates in your blood.

    胰岛素是一种蛋白质,由胰腺细胞分泌,随着血液不断在体内循环

    耶鲁公开课 - 生物医学工程探索课程节选

  • Well, if this kinase happens to turn this protein on then you would like to have a mechanism to turn it off as well.

    那么在激酶激活蛋白质后,你会希望有一种方法能够使它失活

    耶鲁公开课 - 生物医学工程探索课程节选

  • An alternate way is to go to the cell that's making the protein that you want.

    一种方法是,找到制造你想要的蛋白质的细胞

    耶鲁公开课 - 生物医学工程探索课程节选

  • Enzymes work best, enzymes are proteins that catalyze chemical reactions and our bodies operate by elaborate networks of chemical reactions, When we're off from that temperature then they don't work properly.

    举酶这个例子再好不过,酶是一种具有催化作用的蛋白质,人体依靠精密复杂的化学反应网络来运转,如果我们体温与之相差较大,这些酶就不能正常工作

    耶鲁公开课 - 生物医学工程探索课程节选

  • So, a protein that has tyrosine and it has tyrosine in a position such that it's on the outside of the protein and accessible to chemical reaction can be phosphorylated.

    所以,一种蛋白质中含有酪氨酸,并且该酪氨酸位于,像蛋白质的外侧这样的位置,这样才能够发生磷酸化反应

    耶鲁公开课 - 生物医学工程探索课程节选

  • That cutting is done by special proteins called restriction enzymes.

    切割是由一种特别的蛋白质完成的,称为限制性内切酶

    耶鲁公开课 - 生物医学工程探索课程节选

  • For now, just picture it in this simple way as a molecule, usually a protein, that's embedded in the cell membrane and many receptors have a part of them that is extracellular.

    现在,我只把这分子图示出来,受体通常是一种蛋白质,它们镶嵌在细胞膜上,很多受体还有部分结构露在细胞外

    耶鲁公开课 - 生物医学工程探索课程节选

  • So, you cross link all the proteins in the virus, and you make a particle that looks like a virus but it can't act like a virus any longer because it can't replicate.

    当病毒中所有的蛋白质交联后,就得到了一种看上去像病毒,却无法致病的病毒,因为这病毒不能进行复制

    耶鲁公开课 - 生物医学工程探索课程节选

  • We're going to talk a lot about antibodies over the next week or so, but antibodies are specialized proteins that, as you know, are designed to bind to antigens or foreign molecules inside the body.

    我们将会在接下来的几周,讲许多关于抗体的内容,抗体是一种特殊蛋白质,众所周知,抗体用于结合身体内的抗原和外源分子

    耶鲁公开课 - 生物医学工程探索课程节选

  • This involves mechanisms that are still being understood, but if you've studied some biology or read about this you've heard about the protein complex called Dicer.

    人们仍然不太了解这其中的机制,但如果你学过些生物学,或者读到过有关内容,你会听说过一种,叫做Dicer的蛋白质复合体

    耶鲁公开课 - 生物医学工程探索课程节选

  • In this same way, this process of transcription which is occurring in cells throughout body all the time is made possible by a protein called RNA polymerase.

    NA的合成也很类似,身体内每个细胞内,转录过程的进行都是在一种称作,RNA聚合酶的蛋白质催化下进行的

    耶鲁公开课 - 生物医学工程探索课程节选

  • Restriction enzymes are just a kind of enzyme, enzymes are protein molecules that make a chemical reaction go faster, and the chemical reaction that restriction enzymes do is cutting DNA.

    限制性内切酶是一种酶,而酶是加速化学反应的蛋白质分子,限制性内切酶加速的化学反应,是切割DNA

    耶鲁公开课 - 生物医学工程探索课程节选

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