• We know now that it's caused by a related virus, called vaccinia, remember the virus that causes smallpox is called variola.

    我们现在知道这病由一种相关的病毒引起,这种病毒叫牛痘病毒,想想天花病毒也被叫做牛痘病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • They're going to release a viral agent that will kill half of this country.

    他们会释放出一种病毒,让这个国家半的人丧命。

    There is 实战 - SpeakingMax英语口语达人

  • So, this is a cell that's infected with a microorganism, it's infected with a virus, let's say it's infected with influenza virus.

    这是个感染了微生物的细胞,它感染了一种病毒,就说是感染了流感病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • This is a life cycle of a particular class of viruses called retroviruses.

    这里是称为逆转录病毒一种特殊病毒的,生命周期

    耶鲁公开课 - 生物医学工程探索课程节选

  • And so in the 1940s, a group of people led by Collier started to develop a large scale production method for making a reliable source of vaccinia virus.

    在二十世纪四十年代,科利尔带领群人开始研究,一种大规模的生产方法,这方法能制得牛痘病毒的可靠来源

    耶鲁公开课 - 生物医学工程探索课程节选

  • So, you cross link all the proteins in the virus, and you make a particle that looks like a virus but it can't act like a virus any longer because it can't replicate.

    病毒中所有的蛋白质交联后,就得到了一种看上去像病毒,却无法致病的病毒,因为这种病毒不能进行复制

    耶鲁公开课 - 生物医学工程探索课程节选

  • And they also developed a very reliable way for introducing the virus, so that when they had a defined preparation of virus, then you want to make sure that everybody gets it in their skin in the right way.

    他们还发明了一种可靠的方法来引入病毒,当人们有了确定的病毒制剂之后,就要要保证这些制剂都以正确的方式,注射至皮下

    耶鲁公开课 - 生物医学工程探索课程节选

  • Particularly, if we took advantage of the fact that this is a virus that's easily transmitted orally and could you make a vaccine that would be effective orally as well, that would be a tremendous advantage, especially in children who don't like to get shots.

    尤其是,如果我们可以利用这种病毒,很容易经口传播这事实,制造出一种,可以通过口服而起到同样效果的疫苗,那么这将是个巨大的飞跃,特别是对于那些不喜欢打针的孩子

    耶鲁公开课 - 生物医学工程探索课程节选

  • You know about retroviruses, the most famous and important one at this time is HIV, which is a retrovirus.

    你们应该听过逆转录病毒吧,现下最为知名而重要的 HIV,就是一种逆转录病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • HIV is a member of the family of viruses called retroviruses, and retroviruses all use RNA as their genetic material.

    IV是一种逆转录病毒,所有逆转录病毒均以RNA作为遗传物质

    耶鲁公开课 - 生物医学工程探索课程节选

  • This might be a polio virus, for example. The example I've given here is a virus that contains DNA as its genetic material.

    例如 这个应该是,小儿麻痹症病毒,我曾在这里展示过,一种将DNA作为遗传物质的病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • Remember that the lucky thing about the smallpox vaccine was that a naturally occurring attenuated form of the smallpox virus variola called vaccinea was found.

    对于天花病毒来说,幸运的是,存在一种自然发生的,被称作痘苗病毒的,天花病毒的衰减疫苗

    耶鲁公开课 - 生物医学工程探索课程节选

  • We've talked about killing a virus by cross-linking it, for example, to make a substance that looks like a vaccine-- looks like a virus but can't replicate.

    例如,我们谈论过,通过蛋白交联来杀死病毒,以便制造出一种类似疫苗,应该是类似病毒但却无法进行复制的物质

    耶鲁公开课 - 生物医学工程探索课程节选

  • In many cases, it affects--it also initiates its infection through the gut.

    在很多情况下,它也同样是一种经消化道感染病毒

    耶鲁公开课 - 生物医学工程探索课程节选

  • HIV, HIV is a natural virus that contains an enzyme in it.

    IV,HIV是一种自然病毒,里面有一种

    耶鲁公开课 - 生物医学工程探索课程节选

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