Therefore, it has attracted extensive attention to develop new potent macrolides against resistant bacteria.
因此，开发新的抗耐药菌大环内酯抗生素已成为当前药物研究的热点。
Objective to investigate the macrolides resistant phenotype and genotype in Streptococcus pyogenes.
目的研究酿脓链球菌对大环内酯类抗菌药物的耐药表型与基因型。
Tetracyclines macrolides and quinolones are the effective antibiotics in the treatment of these diseases.
四环素类、大环内酯类、喹诺酮类抗生素是治疗解脲支原体感染的主要有效药物。
ABSTRACT Objective to investigate the macrolides resistant phenotype and genotype in Streptococcus pyogenes.
目的研究酿脓链球菌对大环内酯类抗菌药物的耐药表型与基因型。
It has been reported that many macrolides antibiotics may affect functions of neutrophil and induce its apoptosis.
研究证实，多种大环内酯类抗菌素能影响中性粒细胞的功能，并诱导其凋亡。
METHODS: By collecting the literatures and making aggregate analysis of 8 representative drugs depending on the classifications of macrolides, quinolones and tetracyclines.
方法：查阅相关文献，按大环内酯类、喹诺酮类、四环素类分类对8种代表药物进行综合分析。
The mechanism of macrolide's action indicates that the binding sites of macrolides are located inside the nascent peptide exit tunnel of the ribosomal 50S subunit near the peptidyl transferase center.
抗菌机制研究表明：大环内酯抗生素的作用靶点位于50S亚基肽通道的出口处，紧邻肽酰转移酶中心。
Macrolides are the effective antibiotics in the treatment of MP infection.
大环内酯类抗生素是治疗MP感染的有效抗生素。
Macrolides are the effective antibiotics in the treatment of MP infection.
大环内酯类抗生素是治疗MP感染的有效抗生素。
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