PIP2 binds directly to ion channels and modulates their activity.
磷酯酰肌醇二磷酸直接结合离子通道和调节它们的行为。
Many biological processes depend on the ability of ion channels to regulate the flow of ions through cellular membranes.
许多生物学过程依赖离子通道的这种能力来调节通过细胞膜的离子流。
In the future, they hope to use their research on ion channels to better understand the kinds of electrical malfunctions that cause disorders like epilepsy.
他们希望在将来能通过对离子通道的研究更好地理解人类身体电故障的原因。这类故障会导致癫痫等人类机能失调。
And all ion channels are selective for a single type of ion, and we can think about how that selectivity takes place, and that's where this idea of atomic radius is going to become very important.
所有的离子通道都是仅对某一种离子具有选择性的，而我们可以来想一想这种选择性是如何发生的，这也就是原子半径这个概念将会变得，非常重要的地方。
Researchers have engineered a benign virus that, when injected into the brain, makes the ion channels—the switches that turn cells on and off—responsive to light.
研究人员在小鼠脑内注入某种良性病毒，这种病毒使细胞膜上和细胞兴奋有关的离子通道对光产生反应。
Another source of information is genetic. Long QT syndrome is caused by defects in ion channels, proteins that maintain heartbeat by controlling the flow of ions across the membrane of heart cells.
长qt综合征的另一个来源是遗传，长qt综合症是由离子通道的变异引起的，蛋白质通过控制离子流经细胞薄膜来维持心跳。
Ion channels sit in a cell's outer membrane and let electrically charged atoms (ions, as they are known in chemical jargon) in and out of the cell.
离子通道位于细胞外膜，使带电荷原子(即化学术语中的离子)可以进出细胞。
Ion channels are known to regulate signaling between such neurons.
而离子通道已知能够调节神经元之间的信号。
It is likely that the genes involved, which include genes that encode neuronal ion channels, have been subject to a positive selection pressure leading to an accelerated evolution of genetic changes.
与之其进化相关的基因，包括编码的神经离子通道的基因，可能受到了积极的选择压力，从而加速了基因变化的转变。
And when we talk about any type of ion channel, there are just tons of different kinds of ion channels, and you can characterize them in a few different ways.
而当我们讨论任何一种离子通道时，离子通道有非常多种，你可以用几种不同的方法来描述它们。
"If there is a slight mutation in the ion channels in your heart, that's very likely to be a fatal mutation," Markham said.
马克·汉姆表示：“人类心脏的离子通道发生细微变化都很可能是致命的。”
many of these ion channels have this size exclusion pore, it's a very important part of them.
很多离子通道也都有这样的具有尺寸排斥性的小孔，这是它们非常重要的组成部分。
Arnsten said that the aging prefrontal cortex appears to accumulate excessive levels of a signaling molecule called cAMP, which can open ion channels and weaken prefrontal neuronal firing.
Arnsten认为，衰老的前额叶皮层中积累了过多的信号化学分子，称为环腺苷酸(Camp)，它能打开离子通道，从而削弱前额叶皮层中神经元放电的频率。
A living cell is a complicated mess of enzymes, ion channels, messenger molecules and voltages.
活细胞是一个复杂的酶，离子通道，信使分子和电压的集合。
Mutations in ion channels are likely to be involved in epilepsy, chronic pain, neurodegenerative diseases and muscular diseases, and ion channels are the target of many drugs.
癫痫，慢性疼痛，神经变性疾病，和肌肉疾病可能都涉及到离子通道的突变，并且离子通道是许多药物的靶点。
The company has its focus on nucleotide chemistry with special emphasis on cyclic nucleotide-based modulators of respective protein kinases, phosphodiesterases and ion channels, etc.
公司主要关注核苷酸化学，尤其侧重环状核苷酸为基础的各种蛋白激酶、磷酸二酯酶和离子通道等的抑扬调节剂。
Initially molecular biology enriched our understanding of ion channels and receptors important for signaling.
分子生物学自始就丰富了我们对离子通道和信号转导中重要的受体认识。
As the member of transient receptor potential family of ion channels, vanilloid receptor is the new target against pain.
香草酸受体是瞬时受体电位离子通道家族中的成员，为治疗疼痛的新靶点。
The widely using of patch clamp technique has greatly promoted our knowledge of ion channels.
膜片钳技术的广泛应用极大推动了人们对离子通道的认识。
AT-1 cells possess many features typically seen in cardiac cells from other species, such as spontaneous beating, multiple ion channels and responses to drugs, etc.
AT 1细胞具有许多其他动物心脏细胞的典型特征，例如自发性搏动，多种离子通道和对许多药物起反应等。
Here we show that cholesterol regulates the submembrane pool of ion channels readily available for recruitment into the surface membranes of heart cells.
我们的研究证实胆固醇可以调节离子通道亚膜池使之随时补充心肌细胞表面膜结构。
Results: (1) Whole-cell patch-clamp recording technique was established, and highly stable whole cell ion channels' current curves of normal ventricular myocytes were ploted.
结果：(1)建立了膜片钳全细胞记录技术平台，获得了高稳定性的正常心室肌细胞全细胞离子通道电流图。
This paper summarized the type and function and method of research and the relation with disease of cyclic nucleotide-gated ion channels.
文章综述了环核苷酸门控离子通道的类型、功能、研究方法及其与疾病的关系。
Electrophysiological studies have shown that ion channels play an important role in mineral uptake, translocation and salt resistance.
电生理学的研究表明，根细胞离子通道对于矿质吸收、转运及植物耐盐具有重要作用。
In the past two decades, at least 30 kinds of ion channels in the membrane of neurons have been observed to be sensitive to general anesthetics at clinical relevant concentrations.
在过去的二十年中，人们先后观察到近30种存在于神经元膜上的离子通道受到临床浓度全麻药的调控。
In the article the effect of thyroid hormones was reviewed on cardiac ion channels and transports, so as to explain the changes of the action current on cardiac myocyte.
本文综述了甲状腺素对心脏离子通道和转运装置的作用，解释了其引起心肌细胞动作电位变化原因。
The ion channel behaviors of three modified GCEs were investigated under the same conditions to show the similarities and the differences of the ion channels.
将三种修饰电极在不同条件下的离子通道行为对比，分析离子通道行为的相似性和差异性。
CONCLUSION IL possesses the antagonistic effects on stretch-induced arrhythmia, which may be related to blockade of stretch-activated ion channels.
结论：IL具有拮抗牵张性心律失常作用，这种作用可能是通过阻断牵张活化的离子通道实现。
CONCLUSION IL possesses the antagonistic effects on stretch-induced arrhythmia, which may be related to blockade of stretch-activated ion channels.
结论：IL具有拮抗牵张性心律失常作用，这种作用可能是通过阻断牵张活化的离子通道实现。
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