Interleukin-12 (IL-12) is a recently characterized heterodimeric cytokine composed of two subunits.
白细胞介素-12是一种异二聚体细胞因子。
Thus, IL-12 is a crucial bridge between innate and adaptive immunity.
因此,IL ? 12被成为天然免疫和获得性免疫之间的桥梁。
Conclusion Ganoderan can inhibit the excretion of IL-12 in adjuvant arthritis rats serum.
结论灵芝多糖可明显抑制佐剂性关节炎大鼠血清il - 12的分泌。
Objective: To study the change of plasma level of IL-12 in patients with severe thermal injury.
目的:研究严重烧伤后血浆IL-12浓度的变化及其意义。
Conclusion The two subunits of IL-12 are successfully linked with linkage peptide by using this method.
结论:利用该基因分子拼接技术成功地将人白介素12两个亚基基因通过连接肽基因进行拼接。
Results: IL-12 and IL-18 induced prominent spleen deficiency syndrome similar with that induced by reserpine.
结果:IL - 12及IL - 18引起明显脾虚证的表现,与利血平制作脾虚动物模型组相似。
Objective: To study the clinical significance of serum interleukin-12 (IL-12) in patients with viral hepatitis.
目的:探讨病毒性肝炎患者血清中il - 12的改变及其临床意义。
To explore the changes of NK, IL-12 and CRP levels in pregnancy with preeclampsia and its clinical significance.
目的测定子痫前期孕妇外周血nk、IL - 12、CRP水平的变化并探讨其意义。
The therapeutic effect of sinomenine on rheumatoid arthritis may be related to its inhibition to secretion of IL-12 in DCs.
青藤碱的抗类风湿作用可能与其抑制树突状细胞分泌白细胞介素12有关。
Levels of serum IL-12 in early stage helps us in prognosticating the disease and guiding in clinical diagnosis and treatment.
早期检测血清il - 12水平,可判断病情的预后,并指导临床的诊断及治疗。
Objective To detect the level of interleukin(IL-10)and IL-12 in the serum of patients with atopic dermatitis and investigate the role of them.
目的研究血清中白介素-10(IL-10)及白介素-12(IL-12)水平与异位性皮炎的关系。
Objective To study the method of immunotherapy against t cell lymphoma by tumor cells transfected by GM-CSF gene combined with interleukin 12 (IL-12).
目的探讨用转粒细胞巨噬细胞集落刺激因子(GM CSF)基因瘤苗,联合白介素12 (IL 12)治疗小鼠t细胞淋巴瘤的方法。
"These results suggest that therapeutics that target the IL-12 and IL-23 signaling pathway appear to effectively treat both psoriasis and IBD," he said.
“这些结果提示了针对白介素- 12和白介素- 23信号通路的治疗方法可能对银屑病和IBD均有效。”他说。
Objective To examine the in vitro antitumor activity of normal human peripheral blood mono-nuclear cells(PBMC) induced by interleukin-2(IL-2) and IL-12.
目的检测白细胞介素-2(IL-2)联合IL-12诱导人外周血单个核细胞(PBMC)体外抗肿瘤作用。
Abstract: Objective to investigate the effect of IL-12 on mediator release from mast cells and the potential signal transduction pathways correspondingly.
目的:检测IL - 12对肥大细胞介质分泌的影响并探讨其可能的信号转导通路。
Objective To investigate the treatment of spontaneous metastatic lung cancer by tumor antigen-pulsed, interleukin-12(IL-12) gene-modified dendritic cells (DC).
目的探讨肿瘤多肽致敏的白介素12 (IL 12 )基因修饰的树突状细胞(DC)对自发性肺转移癌的治疗作用。
Objective To investigate the antitumor activity of cord blood mononuclear cells(CBMC) activated by interleukin-2 (IL-2)in combination with interleukin-12 (IL-12).
目的探讨白细胞介素-2(IL-2)联合白细胞介素-12(IL-12)对人脐血单个核细胞(CBMC)抗肿瘤作用的影响。
In summary, IL-12 cytokine family plays distinct roles in anti-tumor immune responses and has become a focus of study in the research and immune therapy of tumors.
总之,IL - 12细胞因子家族成员在肿瘤免疫反应中各自发挥不同的作用,已成为肿瘤免疫治疗和研究的热点分子。
Objective To observe the influence of ultraviolet C(UVC) irradiation on apoptosis of human peripheral blood monocytes and interleukin-2(IL-2), interleukin-12(IL-12).
目的观察短波紫外线(UVC)照射正常人外周血单个核细胞凋亡及白细胞介素2(IL- 2) 、IL- 12 水平的影响。
A study is intensively made about the influence of the culture conditions for a lactic acid bacterium on the activity of promoting the production of IL-12 from a murine splenic cell.
本发明针对乳酸菌的培养条件对来自小鼠脾细胞的IL-12的产生促进效果的影响进行了锐意研究。
Objective: to measure the expression of IL-23 and IL-12 in mice with disseminated candidiasis, in order to understand the role of IL-23 in the anti-systemic Candida albicans infection.
目的了解系统性白念珠菌感染小鼠il - 12和IL - 23的表达特征,探讨IL - 23在抗白念珠菌系统感染中的作用,并重新认识和评价IL - 12的作用。
Objective: to observe the expression of GATA-3in asthmatic mice lungs and to explore the feasibility of interleukin (IL-12) blockading GATA-3expression in treatment of bronchial asthma.
目的观察t细胞特异转录因子gata - 3在支气管哮喘(哮喘)小鼠肺部的表达,探讨应用白细胞介素12 (IL - 12)阻断GATA - 3表达治疗支气管哮喘的可能性。
Interleukin-12 (IL-12) previously called cytotoxic lymphocyte maturation factor (CLMF) or NK cell stimulatory factor (NKSF) is a recently characterized heterodimeric cytokine composed of two subunits.
白细胞介素-12(IL-12)最初称作自然杀伤细胞刺激因子(NKSF)或细胞毒性淋巴细胞成熟因子(CLMF),是一种异二聚体细胞因子。
The main Indian contingent will comprise 33 officers and 65 personnel below officer rank, while the support team of IL-76 and IL-78 MKI include an additional 12 officers and 26 others.
印度主要的特遣队将包括33名军官和65名军官以下级别的人员,同时IL-76和IL-78MKI的支持团队将包括额外的12名军官和26名其他人员。
Objective To investigate the effect of IL 12 antisense oligonucleotides on immunoglobulin secretion by PBMC from patients with active lupus nephritis (LN).
目的探讨IL 12反义寡核苷酸对狼疮肾炎(LN)患者单个核细胞(PBMC)分泌免疫球蛋白的影响。
Objetive to construct human IL 12 efficient expression vector.
目的构建人il - 12的高效表达载体。
Objectives To establish the mouse heart transplantation model and observe the effect of anti rejection of IL 12 antibody.
目的建立小鼠心脏移植模型,观察白细胞介素12 (IL 12)抗体的抗排斥作用。
Methods: the rats were immunized by the major surface glycoprotein (MSG) of Pneumocystis carinii combined with IL - 12 as an adjuvant.
方法:用IL - 12作为佐剂和卡氏肺孢子虫主要表面糖蛋白(MSG)一起免疫大鼠。
Conclusion Local administration of IL 12 into the portal system would be a useful strategy for the liver metastasis treatment.
结论通过门静脉系统局部应用IL 12是治疗肝转移肿瘤的有效方法。
Conclusion Local administration of IL 12 into the portal system would be a useful strategy for the liver metastasis treatment.
结论通过门静脉系统局部应用IL 12是治疗肝转移肿瘤的有效方法。
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