In commenting on the study, Dr. Libby emphasized its importance, but echoed Dr. Despres' caution that a limitation of the study is its use of biomarkers to measure risk rather than hard end points.
在对本文的评论中，Libby博士强调其重要性，但despres博士认为这项研究的局限性是它使用的是生物标志物来衡量其风险，而不是硬终点。
I know it's the end of high school, but many of classmates are going on to the same university, and we are still required to study hard.
我知道高中已经结束了，但是很多同学将上同一所大学，我们仍然需要努力学习。
The students have been working hard on their lessons and their efforts will be rewarded with success in the end.
学生们一直在努力学习功课，他们的努力终将获得成功。
At the end of the day, if you move this metal thing aside with your fingers, don't squeeze it too hard.
在一天结束的时候，如果你用你的手指把这个金属块移到一边，不要用力捏它。
Times were hard at the end of the war.
战争后期生活很艰苦。
All my hard work paid off in the end, and I finally passed the exam.
我的所有努力最终得到了回报，我终于通过了考试。
In the longer term, such children end up lonely, dependent, chronically dissatisfied and resentful of the parents who tried so hard to please them.
长远来看，这样的孩子最终会变得孤独、依赖性强，慢慢地对努力取悦他们的父母变得不满和怨恨。
Patterns of childhood eating can be hard to break when we're adults, which may mean that kids of depressed moms end up dying younger.
童年的饮食模式在我们成年后很难打破，这也许意味那些有着抑郁的母亲的孩子们最后会早逝。
At the end of the day, you really do need to work hard and get really, really good at what you do.
最后，你真的需要努力工作，才能把你所做的事情做得非常非常好。
The life is hard for my father: my mother died years ago, and now his children are far from home, our selfish choices taking us from one end of the country to the other.
我父亲的生活很艰难：我母亲多年前就去世了，现在他的孩子们远离家乡，我们自私的选择把我们从国家的一端带到另一端。
Success belongs to the hard-working people in the end.
成功最终属于努力的人们。
I was often sad, and saw no end to "the hard times".
我常常感到悲伤，觉得“困难时期”看不到头。
It took a lot of research and hard work to go from the Apple Newton to iPhone but in the end, the effort became successful.
从苹果牛顿到 iPhone，苹果公司付出了大量的研究和努力，但最终努力换来了成功。
It's hard work but if you hang on you'll succeed in the end.
这是件困难的工作，但如你坚持不渝，最后是能成功的。
It's hard to see the end in sight, and there are sleepless nights peppered in our work weeks because of sick kiddos, nursing infants, or willful toddlers.
看到尽头是困难的，因为要生病的家人、需要照顾得婴儿或者任性的孩子，无眠的夜晚布满我们的工作周。
But you should run hard enough at the end to accustom your body to the late-race fatigue of the marathon.
你应该在将近结束时跑得卖力一点，这样会使你的身体适应马拉松比赛时后期的疲惫感。
At the end of a hard day it can sometimes feel like gadgets such as phones and computers are sapping our energy.
在疲惫的一天结束之时，有时我们会感到手机电脑等设备好像正不断地抽走我们的精力。
No memory of having starred Atones for later disregard Or keeps the end from being hard.
没有关于补偿,随后的漠视,或是冷酷的尽头的任何记忆。
A boom must end eventually, they learned the hard way, and spending alone cannot build Jerusalem.
他们付出惨痛的代价终于明白：繁荣必将结束，耶路撒冷并非单靠花钱建立起来得。
The end is hard and it's going to be hard, no matter how you come to it.
结束很难，并且一定会很难，无论你打算怎样结束。
But I want to end by mentioning the hard problem as it is known now.
最后，我想再讲一个众所周知的难题。
We had been working so hard, after the end of the war. For 60 years.
二战后的六十年中，人们一直在努力工作。
And I think that we will one day live without fear because right now, survivors, families, doctors, nurses, researchers, and advocates are all hard at work trying to end this disease.
我认为，我们将来有一天在没有恐惧之中，因为现在，幸存者，家属，医生，护士，研究人员和倡导者的工作都努力试图结束这种疾病。
Work hard, but remember to play as well or you'll end up miserable.
努力工作，但是要记住也要娱乐，或者结束你的痛苦。
But all of us - volunteers, workforce, everybody involved - has to keep their eye on the ball, work hard right to the end.
不过，我们所有人，不论是志愿者、工作人员，参与冬奥会的各个方面都要保持警觉，努力工作到奥运结束。
New school: If you want to finish strong and improve your times in the marathon, you have to run hard and fast at the end of your long runs.
现在的学校，如果你想要变得结实强壮点，提高你的马拉松成绩，那你必须在长跑结束时跑得卖力点快一点。
If you want to lose weight or gain muscle, you need to train hard for weeks on end to see results.
如果你希望减轻体重或者增长肌肉，你需要去刻苦地训练几周然后才能看到结果。
And seen from this end of the century it's not hard to see why.
从本世纪末的目标中，就不难看出这是什么原因。
The eggs would be hard boiled by the music before the end of the concert and could be eaten.
在音乐会结束之前，这些鸡蛋已被音乐煮熟，然后孩子们会把它们吃掉。
Often, when we are at one end of the spectrum, it's hard to remember the other end.
常常，当我们处在一个极端的时候，我们很难回忆起另一个极端。
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