FOXP3 may provide a new target for immunotherapy of astrocytic tumors.
FOXP3可能成为星形细胞肿瘤免疫调节的新靶点。
We and others have evidence that Foxp3 is also inhibiting that protein.
我们和其他研究人员发现Foxp3也可以抑制此蛋白。
Conclusions: FOXP3 expression in human cells is affected by T-cells activation.
结论:人类FOXP3的表达受T细胞活化影响。
The other thing will be to look for chemicals that mimic the function of Foxp3.
另外一件事是寻找模拟Foxp3功能的化学物质。
So, we could hypothesis that FOXP3 might play an inhibitory role in gastric cancer immune escape.
综上所述,我们发现FOXP3可能在胃癌的免疫逃逸过程中发挥重要功能。
Intrahepatic FOXP3 levels are associated with HCV reinfection, a history of acute rejection, and increased within the first year after LTx.
肝内FOXP3水平与HCV再感染和急性排斥史有关,且在肝移植后第一年升高。
It is believed that FOXP3+CD4+CD25+T can regulate the immune suppression and inability, and it is highly expressed in many kinds of malignant tumors.
FOXP3+CD4+CD25+T细胞是调节机制免疫抵制及免疫无能的一类细胞,在许多人类恶性肿瘤组织中有较高表达,且在肿瘤的发生及进展中起着重要的作用。
Results: FOXP3 expression in tumors was associated with worse overall survival probability and the risk increased with increasing FOXP3 immunostaining intensity.
结果:FOXP3在肿瘤细胞中的表达与较差的总生存期有关,而且增加了FOXP3免疫染色强度。
Purpose: The transcription factor forkhead box P3 (FOXP3) up- or down regulates a large number of genes and has been recently reported to be expressed in tumor cells.
目的:头叉转录因子箱(FOXP3)---调控大量基因的表达而且有报道说已在肿瘤细胞中有表达。
If you find some secret sauce that will modify Foxp3's activities and you've shown that this is critical to a broad spectrum of disorders, that's going to be a great thing.
如果你发现了修饰Foxp3活性的秘方并提示对一系列病症能起关键作用的话,那将是一件很了不起的事情。
If you find some secret sauce that will modify Foxp3's activities and you've shown that this is critical to a broad spectrum of disorders, that's going to be a great thing.
如果你发现了修饰Foxp3活性的秘方并提示对一系列病症能起关键作用的话,那将是一件很了不起的事情。
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