Objective: To synthesize valdecoxib, a COX-2 inhibitor.
目的：合成COX-2抑制剂戊地昔布。
No COX-2 immunoreactivity was observed in normal cerebellar tissue.
正常小脑组织标本中未发现COX - 2的表达。
COX-2, which is the inducible form, involved in inflammation and cancer incidence.
COX - 2是环氧化酶的诱导型，参与炎症反应和肿瘤的发生。
In contrast, with absent or weak COX-2 tumors, regular or nonregular use of aspirin made no difference.
相反，COX - 2不表达或表达较弱的肿瘤，定期或不定期使用阿斯匹林没有差别。
COX-2 plays an important role in the growth of tumour cells, apoptosis, and the angiogenesis of tumour.
COX - 2在肿瘤细胞生长、细胞凋亡和肿瘤血管生成方面发挥重要作用。
This research adds to the growing evidence for a possible role for COX-2 inhibition in various cancers.
本研究为COX-2阻断剂治疗多种癌症的作用提供了进一步的证据。
Similar to immortal cells, the majority of breast cancer cell lines expressed low levels of COX-2 protein.
与这些细胞相似的是，COX - 2在绝大多数乳腺癌细胞系仅有很低程度的表达。
Nor does it mean that COX-2 inhibitors, which repress COX-2 activity, will necessarily lead to weight gain.
也不意味着COX - 2抑制剂，抑制COX - 2活性，就必然会导致体重增加。
Aim: To study the effect of chronic hypoxic hypercapnia on expression of COX-2 mRNA in pulmonary arterioles.
目的：研究慢性低氧高二氧化碳对大鼠肺动脉环氧酶- 2 (COX - 2)基因表达的影响。
Selective COX-2 inhibitors could suppress the proliferation and induce apoptosis of bladder cancer cell line.
选择性COX - 2抑制剂体外可抑制膀胱癌细胞的增殖，并诱导细胞凋亡。
CONCLUSIONS: Selective COX-2 inhibitor could inhibit the proliferation and induce the apoptosis of T24 cells.
结论：选择性COX - 2抑制剂体外可抑制T24细胞的增殖，并诱导细胞凋亡。
Objective To study the expression of cyclooxygenase -2 (COX-2) in skin carcinoma and its clinical significance.
目的探讨环氧合酶2 (COX 2)在皮肤肿瘤组织中的表达及其临床意义。
Objective To explore the effect of cyclooxygenase 2 (COX-2) in the pathogenesis of alcoholic liver disease (ALD).
目的探讨环氧合酶2 (COX - 2)在酒精性肝病(ALD)发病机制中的作用。
Objective To explore the relationship between COX-2 expression and angiogenesis in salivary gland adenocarcinoma.
目的探讨环氧合酶- 2 (COX - 2)表达和涎腺腺癌血管生成的关系。
Conclusion The patients with COX-2 positive expression possibly have axillary lymph node metastases of breast cancer.
结论：COX - 2阳性表达的患者可能易发生乳腺癌腋窝淋巴结转移。
Objective To study the expression of cyclooxygenase-2 (COX-2) and HER-2 in human breast cancer and their relationship.
目的研究环氧化酶2 (COX 2)和表皮生长因子2 (HER 2)在乳腺癌中的表达及其相关性。
Objective To review the research progress of selective cyclooxygenase-2 (COX-2) inhibitors and anti-inflammatory herbs.
目的介绍选择性环氧化酶（COX）-2抑制剂与抗炎植物药研究概况。
Recent studies implicated expression of cyclooxygenase 2 (COX-2) as a marker to identify precursor cells for breast cancer.
最近的一些研究表明环氧化酶2 (COX - 2)的表达可以作为发现乳腺癌细胞的标记。
COX-2 inhibitors are powerful anti-inflammatories, but synthetic forms of COX-2 inhibitors have caused numerous side effects.
COX-2抑制剂是种非常有效的抗炎物质，但是人工制造的COX-2抑制剂会导致许多的副作用。
Another limitation, they noted, was the lack of a standardized classification system for COX-2 expression in colorectal cancer.
他们指出，另一个限制因素是，对COX - 2在大肠癌中的表达缺乏一个规范的分类体系。
Objective to clarify whether proton pump inhibitors (PPIs) stimulate Cyclooxygenase-2 (COX-2) expression in rat gastric mucosa.
目的探讨质子泵抑制剂(PPI)对大鼠胃粘膜环氧化酶—2 (COX - 2)表达的影响。
Objective: To investigate the expression of COX-2 and MMP-7 and their influence on invasion and metastasis in colorectal cancer.
目的：探讨结直肠癌环氧化酶- 2和基质金属蛋白酶- 7的表达与侵袭、转移的关系。
Methods The expression of COX-2 was determined by immunohistochemistry in 45 cases of malignant melanoma and 25 intradermal nevi .
方法免疫组化法比较性研究25例皮内痣、45例恶性黑素瘤COX-2蛋白的表达情况。
Objective To investigate the expression of Cyclooxygenase-2 (COX-2) and its prognostic significance in oral squamous cell carcinoma.
目的调查环氧化酶- 2 (COX - 2)在口腔鳞状细胞癌中的表达及其预后意义。
OBJECTIVE: To explore the relationship between the expression of COX-2 and pathophysiological features of patients with lung cancer.
目的：探讨肺癌组织中COX - 2的表达及其与临床病理生理特征之间的关系。
Aims To investigate the relationship between COX-2, VEGF expressions and the clinical pathologic characteristics of gastric carcinoma.
目的：探讨COX - 2和vegf的表达与胃癌临床病理特征之间的关系以及COX - 2与VEGF表达的相关性。
In this study we try to elucidate the relationship between expression of 5-lox and COX-2 and neurodegeneration induced by aluminum overload.
在本研究中，我们试图对COX - 2和5 -LO的表达与铝过负荷致神经元退变的关系进行初步研究。方法。
Objective To clarify cyclooxygenase-2(COX-2)expression and the effects of a specific cox-2 inhibitor in the healing of gastric mucosal damage.
目的探讨环氧化酶-2（COX-2）在胃粘膜的表达，和特异性COX-2抑制剂对胃粘膜损伤愈合的影响。
However, it was recently shown that the reproductive defects of COX-2-deficient mice mainly depend upon genetic background of the mouse strains.
最近的研究表明，COX-2基因敲除小鼠的生殖缺陷主要依赖小鼠的遗传背景，与小鼠的品系相关。
However, it was recently shown that the reproductive defects of COX-2-deficient mice mainly depend upon genetic background of the mouse strains.
最近的研究表明，COX-2基因敲除小鼠的生殖缺陷主要依赖小鼠的遗传背景，与小鼠的品系相关。
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