Combinatorial chemistry is used in tandem with high-throughput screening to identify compounds that bind to a therapeutic target protein and are thus potential new drugs.
组合化学与大规模筛选相结合用于识别与治疗用靶蛋白结合的化合物即潜在新药。
Screening for the herbicidal activities of compounds is the first and most important step in developing new herbicides.
化合物的除草活性筛选是开发新除草剂的最初和最重要的阶段。
Screening safe and effective anti-HBV compounds in traditional Chinese medicine provides a large opportunity for the development of anti-HBV drugs.
从中草药中寻找高效低毒的抗HBV单体化合物是发现并研制抗HBV药物的一条有效途径。
The frog embryo extract and screening strategy may also be applied to identifying compounds that modify other developmentally important signaling pathways, Lee added.
蛙胚提取物和筛选策略还可能应用于鉴定其他对早期发育相关信号通路有影响的化合物。
The derived QSAR models further validate the binding model of sulfonylurea compounds and AHAS, and provide a very useful tool in the next virtual screening.
得到的QSAR模型进一步验证了复合物中磺酰脲化合物与酶的连接模式,并为下一步的虚拟筛选提供了一个非常有用的工具。
Meanwhile, we screened 1227 kinds of microbial fermentations, by comparing with the results of synchronous cell-model screening, 6 compounds and 7 fermentation candidates were acquired.
同时对1227种发酵液进行了筛选,并与本室同步的细胞模型筛选结果对比,发现有6个阳性化合物和7株阳性候选发酵液。
Is Chemical Technology engaged in offers building blocks and screening compounds used in drug discovery and pre-clinical development.
IS化工科技从事提供积木和筛选药物发现和临床前开发阶段使用的化合物。
We use traditional enrichment, screening, purification methods to select 10 degrading bacteria of 8 kinds of phenolic compounds from a soil sample polluted by phenol wastewater.
本研究利用传统的富集、筛选、纯化的方法,从受含酚废水污染的土壤中筛选出了8种酚类化合物的10株降解菌。
Results from this study can be used to prioritize the screening of drug-like compounds against the parasite and will be made freely available to the community and collaborating laboratories.
研究结果可以用来优先次序,筛选药物类化合物对寄生虫,将免费提供给社区及协作实验室。
Said invention also relates to methods of identifying or screening active compounds in said pathologies.
本发明同时涉及鉴定或者筛选对这些疾病有活性的化合物的方法。
Syntechem is a dedicated manufacturer of rare and unique chemicals including building blocks and screening compounds from a few grams to metric tonnes scale.
常州欣特科化工有限公司是专业的研究化学品(包括合成砌块和筛选化合物)生产商和供应商。
METHODS a series of pyrrolidine derivatives were synthesized from L-hydroxyproline, and the neuraminidase inhibitory activities of these compounds were tested using high throughput screening.
方法以L -羟脯氨酸为原料,合成一系列神经氨酸酶抑制剂,并用高通量活性筛选方法检测其对神经氨酸酶的抑制活性。
This review summarizes recent progress in drug discovery including identification and validation of novel drug targets, and screening for new therapeutic compounds.
最近的研究还发现,斑马鱼不仅用于新药筛选,还可用于药物结构的优化。本文重点介绍斑马鱼在新药发现中的应用。
Mixing compounds together into pools for screening is one way to accelerate this process and reduce costs.
化合物混合在一起,形成集合筛选的方法之一是加速这一进程,并降低成本。
Abstract: the use of biological transformation of structural modification of natural drugs is one of the effective ways for screening new natural active compounds.
摘要:利用生物转化对天然药物进行结构修饰,是筛选新的天然活性化合物的有效途径之一。
The potential benefit of creatine for PD was identified by Parkinson's researchers through a new rapid method for screening potential compounds.
帕金森病研究者通过一种快速的方法筛选可能的复合物,来明确肌酸对帕金森病的潜在的好处。
The other 10 compounds have been first screened, and 5 of them showed significant activity of promoting nerve growth. Their second screening is doing.
另外10个经过初筛的化合物中有5个具有显著的促神经生长活性,它们正在复筛中。
By employing a combination of structure-based drug design and high-throughput screening approaches, several useful compounds for treating HCV infections have been successfully introduced.
通过基于分子结构的药物设计与高效筛选技术,以及免疫疗法的研究进展,已有若干药物可有效的治疗丙肝。
By employing a combination of structure-based drug design and high-throughput screening approaches, several useful compounds for treating HCV infections have been successfully introduced.
通过基于分子结构的药物设计与高效筛选技术,以及免疫疗法的研究进展,已有若干药物可有效的治疗丙肝。
应用推荐