What we are doing here is precisely matching a treatment to a specific type of cancer cell mutation and abnormal protein signaling pathways that may activate cancer cell growth.
我们在此所做的就是精确匹配治疗方案。一种治疗方案针对一种特殊类型的癌症突变细胞和可能激活癌症细胞生长的异常蛋白信号通路。
Cell affinity, therefore, is an essential part of the DNA and is subject to mutation as much as the letter of the cell is.
因此，细胞关联性是DNA的一个基本部分，和细胞的字母一样受到变异的影响。
Lymphomas, leukemias, malignant melanomas, sarcomas all begin with that microscopic accident, a mutation in one cell: omnis cellula e cellula e cellula.
淋巴瘤、白血病、恶性黑色素瘤和肉瘤都开始于极微小的事件——一个细胞发生了变异（用拉丁语说，就是omniscellulae cellula e cellula）。
It's only when you inherit the mutation from both parents that you get sickle-cell anemia.
只有当你同时遗传了父母双方的突变，你才会患上镰刀状细胞性贫血。
About half of all melanoma patients have a mutated BRAF gene. This mutation tells the cell to continue to grow.
将近半数的黑色素瘤患者都有BRAF基因突变，从而导致黑色素肿瘤细胞继续生长。
The mutation results in a malfunctional protein, which cannot perform its normal task to regulate cell growth or actually induces uncontrolled cell growth.
突变产生异常蛋白，不能行使正常功能调节细胞生长，或引发不可控细胞生长。
The mutation itself is in a gene for a nerve-cell protein of a type known as an ion channel.
变异的基因是编码一种叫做离子通道的神经细胞蛋白质。
Mainly refers to the aging of skin protein synthesis control of gene fragments on the gene mutation, resulting in cell Death and fiber breakage, thus forming.
皮肤的衰老主要指控制蛋白质合成的基因片段上的基因突变，造成细胞的死亡及纤维的断裂，从而形成皱纹。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
虽然许多原癌基因和肿瘤抑制基因被广泛表达，这些基因的突变与特定的器官或细胞类型的癌有关。
Here, we investigate the possibility of whether a tumor cell nucleus, in which transformation is caused by somatic mutation, can be epigenetically reprogrammed into normal tissues.
在这里，我们调查的，是由体细胞突变引起的肿瘤细胞的细胞核，能被后生重编程进入正常组织的可能性。
In the 1950s Anthony Allison, a British biochemist, observed that Africans who carry a single copy of the genetic mutation that causes sickle-cell anaemia are protected against malaria.
英国生化学家AnthonyAllison在20世纪50年代观察到非洲人携带单拷贝的基因突变引起的镰状细胞性贫血保护了他们受到疟疾的侵扰。
Like most cancers, it is thought to begin in a single cell, with a mutation that is not present at birth but that occurs later for some unknown reason.
我们认为该病与大多数癌症一样，是起源于单个细胞突变，但这种突变并不是先天的，而是发生于后天，但原因不明确。
Because the oncogenes had been artificially introduced into those cell lines, the researchers then tested their model in human lung cancer cells with the EGFR mutation.
上述试验是人工将癌基因导入肿瘤细胞株，另外的实验是在具有EGFR突变的肺癌肿瘤模型上进行。
An organism consisting of two or more tissues of different genetic composition, produced as a result of mutation, grafting, or the mixture of cell populations from different zygotes.
嵌合体由两种或两种以上有不同基因结构的组织所构成的有机体，由于突变、嫁接或来自不同合子的细胞群体相混合而产生。
KRAS mutation frequency in tumor tissue, can be predicted non-small cell lung cancer molecular targeted therapy efficacy and prognosis, and molecular inhibitors of RAS genes is still in its infancy.
KRAS基因突变在恶性肿瘤组织中频发，可预测非小细胞肺癌分子靶向治疗的疗效和预后，针对RAS基因的分子抑制剂研究仍处于初级阶段。
One option in future may be to create stem cells from a patient's own tissue, then return these after using gene therapy to correct the genetic mutation that causes sickle-cell disease.
未来一个选择是从患者的组织培养干细胞、经基因疗法纠正导致镰刀形细胞症的遗传变异后再移植给患者本身。
The relation between mutation and DNA damage and cell aging is discussed in this paper.
对降低基因突变和DNA损伤与细胞老化的关系作了讨论。
Methods A simple, rapid and sensitive poly-nuclear cell assay was used to investigate the frequency of HPRT locus mutation.
方法采用多核细胞法研究肿瘤患者外周血淋巴细胞HPRT基因位点的突变频率，并与正常人群进行对比。
Methods HPRT gene mutation frequency was examined by the technique of multinuclear cell assay.
应用多核细胞法检测外周血淋巴细胞HPRT基因突变率。
The positive cells expression of P53 had an important relation to the appearance of EBL. B cells with P53 mutation strain might be a target cell to format tumors.
EBL的发生与突变的P53蛋白过表达有重要关系，携带P53突变株的B淋巴细胞可能是形成肿瘤的靶细胞。
When these genes are mutated the particular cell in which the mutation has arose doesn't stop growing, it keeps going.
当这些基因突变发生在的特殊细胞中，突变产生不段产生，保持下去。
Hence it is suggested that BCMA does not induce notable mutation on the cell.
该试验表明：BCMA无明显致细胞突变作用。
Objective To establish TK gene mutation assay using human lymphoblastoid cell line TK6 and to study the genotoxic mechanism of Vinblastine(VBL).
目的建立用人类淋巴母细胞TK 6检测纺锤体毒物——长春花碱的TK基因突变试验方法，同时探讨长春花碱的遗传毒性分子机理。
Gene mutation makes human cells no longer produce normal CCR5 protein, HIV virus so it can not enter the human cell carrier.
基因突变使得人体细胞不再产生正常的CCR5蛋白质，HIV病毒因此也就没有了可以进入人体细胞的载体。
The pathogenesis of pituitary adenomas is considered to be related with gene mutation, growth factors, cell receptors, transcription factors, and cellular signaling pathways.
目前认为垂体腺瘤的发生与基因突变、生长因子、细胞受体、转录因子和细胞信号通路等有关。
Purpose: To study the effects of Taraxacum mongo on anti-mutation and cell proliferation.
目的：研究蒲公英抗突变作用和对细胞增殖的影响。
When function defects of mismatch repair genes, Cell Showes Genomic instability because of the aggregation of mutation.
错配修复基因功能缺失时，细胞常会因基因突变聚集而表现为遗传不稳定。
This is the first evidence of direct mutation of AKT1 in human cancer tumors: it was discovered in clinical samples from cancer patients, yet has never been detected in cancer cell lines.
这是首次在人类肿瘤细胞中发现AKT1突变的直接证据，结果都是从临床样本中检测到的，而在肿瘤细胞株中尚未报道过此突变。
What's more, different dosed of GOPCcan obviously antagonize the frequency of micronucleus in mice bone marrow cell, implying that GOPC has effect of antagonizing mutation.
经口给予小鼠不同剂量的GOPC，能明显拮抗环磷酰胺所致小鼠骨髓细胞微核率，提示其具有抗突变作用。
What's more, different dosed of GOPCcan obviously antagonize the frequency of micronucleus in mice bone marrow cell, implying that GOPC has effect of antagonizing mutation.
经口给予小鼠不同剂量的GOPC，能明显拮抗环磷酰胺所致小鼠骨髓细胞微核率，提示其具有抗突变作用。
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