Besides, gossypol had similar inhibitory effect on CD69 expression of CD3 - lymphocytes.
此外,棉酚对CD 3-的淋巴细胞CD 69表达也有类似的抑制作用。
Objective: To study the propagation and phenotypes changes of killer cell CD3AK cell activated by CD3 mAb in vitro.
目的:研究肺癌清扫淋巴结的淋巴细胞,经CD 3单克隆抗体激活后的杀伤细胞(CD3AK细胞)在体外的增殖和表型变化。
The increase of CD3 + CD4 -cd8 - cells had correlated with mobilization effect of CD34 + cells into peripheral blood.
在各T淋巴细胞亚群中CD 3 + CD 4- CD 8 -细胞的增加与CD34 +细胞的动员效果间具有统计学意义的相关性。
Objective To analyse the phenotype of immature CD3-CD4-CD8+ murine thymocytes and elucidate their stage of differentiation.
目的分析CD3-CD4-CD8+胸腺细胞的表型特征,阐明其在胸腺发育中所处地位。
The CD3 and CD8 positive cells in the area surrounding the infarction core were round and had two forms:small and big cells;
位于坏死区周围的CD3阳性和CD8阳性细胞主要为圆形,有大细胞和小细胞两种形态;
The recombinant protein could specially react with B7 2 McAb and could stimulate T cell proliferation combined with anti CD3 antibody.
在抗人CD3单抗的协同下,B72胞外区重组蛋白能有效地促进外周血单核细胞的增殖。
Results:IPRS could improve the proportion of CD3+ and CD8+ in the piglets pheripheral blood and boost the production of special antibody.
结果:板蓝根多糖能显著提高仔猪的CD3+、CD8+淋巴细胞的百分数和特异性抗体滴度。
The level of CD3, CD4 of the treatment group were obviously elevated , CD8 was obviously reduced and had significant difference (P<0.05).
全血T细胞亚群治疗组CD3、CD4明显增高,CD8显著降低,较疗前有显著性差异(P<0.05)。
Indeed, of the 16 immunodeficiency viruses the researchers looked at, all but five had nef genes that removed TCR-CD3 from the cell surface.
事实上,在研究人员观察的16种免疫缺陷病毒中,除五种以外,其他十一种都具有各自的nef基因以去除细胞表面的TCR-CD3蛋白。
Conclusions Glucocorticoid receptors are down-regulated in CD3 + t lymphocytes in association with increased adrenal secretion of cortisol in ACLF.
结论慢加急性肝衰竭患者外周血cd3 +T淋巴细胞糖皮质激素受体的下调,与患者升高的皮质醇有关。
The immunogenicity of 12F6 in humans has been reduced though humanization. But the first-dose reaction associated with T cell activation by anti-CD3 Abs still exists.
人源化抗体解决了抗体鼠源性的问题,但CD3单抗激活T细胞引起首剂效应的问题仍然存在。
Methods Expression of CD3, CD4 and CD8 antigen on peripheral blood t cells from 30 cases of hemodialysis and non-hemodialysis patients was evaluated by flow cytometry.
方法应用流式细胞仪法检测30例透析及未透析患者外周血t细胞表面的CD 3、及其亚群cd4及CD 8抗原表达。
The genetically engineered antibodies toward the two drawbacks have made a great breakthrough, and several engineered CD3 antibodies have been used in clinical trials.
针对抗体毒副作用进行的基因工程改造取得一定进展,目前已经有许多CD3抗体进入临床试验。
Objective: To study bidirectional binding ability and immunoactivity of anti-CD3/anti-glioma bispecific antibodies(BsAb) , and to study its effect on T lymphocytes cells.
目的:鉴定自制的抗CD3-抗胶质瘤双特异性抗体(双抗)的双向结合能力,测定其免疫活性及其对T淋巴细胞的作用。
The treated patients with persistent positive RPR within two years had elevated levels of CD3, CD4 and CD8 lymphocytes (P<0.05), but NK cells appeared to be lowered (P<0.05);
经过驱梅治疗但RPR持续阳性两年内的患者CD3、CD4及CD8淋巴细胞数显著高于对照组(P<0.05),NK淋巴细胞显著低于对照组(P<0.05);
The percentages of CD3 + and CD4 + and the numbers of WBC and lymphocytes were significantly lower in Group 3 than in the group of rats that received dexamethasone only(P<0 01).
非治疗组的CD3+和CD4+ 百分率和白细胞数及淋巴细胞数均明显低于单纯地塞米松组(P< 0.01)。
The results showed that the number of CD3+and CD4+cells in the urticaria group was significantly lower than that of control group (P< 0.01), especially in patients with acute urticaria.
结果表明,荨麻疹患者CD3+及CD4 +细胞明显降低,与健康对照组比较差异有非常显著性意义(P<0.01),其中以急性荨麻疹患者CD3+、CD4+改变最为明显。
Using anti-CD3 and anti-CD28 to mimic stimulatory signal I / II, to study their function of activing T cells in order to explore the possible mechanism of immune up and down regulation.
利用CD3/28双抗体模拟第一、二信号的变化探讨免疫上下调节的可能机制,为我们研究输血带来的免疫影响及如何纠正提供可依靠的线索。
Activation of this process in immature T cell by the bindng of the TCR CD3 to self antigens may therefor be the mechanism which produces clonal deletion and consequently self tolerance.
未成熟T细胞通过TCR-CD3 复合物与自身抗原接合激活上述过程可能与克隆清除的形成机制及自我耐受有关。
Results Proliferation of pleomorphic lymphocyte, coagulation necrosis of massive tissue and vaso-infiltration were showed in the NK/T lymphoma; tumor cells were positive for CD3, CD45 and CD56.
结果NK/T淋巴瘤组织结构特点为多形性淋巴细胞增生,大片的凝固性坏死和血管浸润,免疫组化表达CD3、CD45和CD56阳性。
Blood sample was gathered before and 5 days after intervention, testing hemogram, biochemical indexes, NK cells, CD3, CD4, CD8, temperature. Postoperative fever was observed in all the patients.
分别于介入术前及术后5天内采血,检测血象、生化指标、NK细胞、CD 3、CD 4、CD8及患者体温,观察患者术后有无发热现象等。
The latest document of ISO/CD3 9004 provides guidelines to management on how to achieve and maintain success for an organization in a demanding, ever-changing and uncertain business environment.
新版ISO/CD3 9004为组织的管理者提供了如何在快速多变的不确定的环境中,使组织达到并保持成功的指南。
It is essential to bethink of CMV infection when CD3 + t lymphocytes, CD4 + t lymphocytes, CD56 + t lymphocytes, creatinine or alanine aminotransferase of renal transplant recipients are abnormal.
当肾移植受者有CD 3阳性T淋巴细胞、CD 4阳性T淋巴细胞、CD 56阳性T淋巴细胞、血清肌配或谷丙转氨酶的异常时应考虑CMV感染。
It is essential to bethink of CMV infection when CD3 + t lymphocytes, CD4 + t lymphocytes, CD56 + t lymphocytes, creatinine or alanine aminotransferase of renal transplant recipients are abnormal.
当肾移植受者有CD 3阳性T淋巴细胞、CD 4阳性T淋巴细胞、CD 56阳性T淋巴细胞、血清肌配或谷丙转氨酶的异常时应考虑CMV感染。
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