成骨细胞分化所需的第二个重要转录因子是一种具有锌指结构的，对骨形成十分重要的转录因子。
A second important transcription factor required for osteoblastic differentiation is osterix.
窍门就是特定DNA打靶的锌指结构。
The trick was coming up with zinc fingers for the specific DNA target.
锌指蛋白是重要和典型的基因调控蛋白。
Zine finger proteins important and typical proteins for gene regulation.
锌指蛋白是重要的、典型的基因调控蛋白。
Zine finger proteins are important and typical Proteins for gene regulation.
环状锌指蛋白基因HRZ在未培养的外植体中表达。
Hormones are essential for maintaining the expression of HRZ, a ring zinc finger gene.
锌指蛋白；
他还补充说锌指核酸酶可能对一些基因具有不可预知的作用。
He adds that the zinc finger nucleases could have unpredictable effects on several genes.
一些在组织和细胞分化中起重要作用的蛋白质包含锌指结构域。
Some of proteins associated with differentiation and development of cells and tissues contain zinc finger domain.
他们在使烟草细胞接触锌指核酸酶之外，也添加了可增强抗除草剂特性的基因片段。
When they exposed tobacco cells to the zinc finger nucleases, they also added a version of that gene that enhances herbicide resistance.
有两个基因的假定功能分别与质膜内嵌蛋白和ANI类锌指蛋白相关。
Two genes which were involved in plasma membrane intrinsic protein and ANI-zinc finger family protein respectively might be the salt tolerance-related genes.
真核生物中的许多蛋白质分子包含锌指结构区，这类蛋白称为锌指蛋白。
A number of proteins in eucaryon contain zinc finger domains and this class of proteins are called as zinc finger proteins.
锌指蛋白载有一种核酸酶，可以与基因黏附，并使基因永久开启或闭合。
Zinc finger protein contains a DNA enzyme, with the adhesion genes, and genes permanently open or closed.
通常附着在核酸酶上的锌指，称作ZFNs，它负责切断dna的两条链。
Zinc fingers are usually attached to enzymes called nucleases, dubbed ZFNs, which cut both strands of DNA.
后来发现它是一种与胰岛素样生长因子相关的锌指超家族中的金属螯合蛋白酶。
And then it was found that PAPP-A was a zinc-binding matrix metalloproteinase associated with insulin-like growth factor.
已知有许多的转录因子是非常重要的MAPK靶基因，锌指蛋白就是中间的一类。
Many transcription factors are important MAPK targets, and zinc finger protein is one of them.
推定的氨基酸序列含有锌指样结构域、脯氨酸丰富区及脯氨酸、谷氨酰胺丰富区。
The human Hrs also contained a zinc finger like domain, a proline rich region and a proline and glutamine rice region.
锌指是最大的DNA结合蛋白家族，是识别DNA最有效、最成功的一种结构元件。
Within the known classes of DNA binding proteins, the zinc finger is the greatest family and are nature′s most successful designs for DNA?binding proteins.
C2H2型锌指是最普遍的类型，它们作为重要的转录调控因子参与许多的生理过程。
The most common zinc finger gene type is the C2H2 type, which plays an important role in many physiological processes as transcriptional regulators.
一种转录因子，其分子内部由于锌指离子的存在而形成多肽链内部的折叠，呈手指状突起。
Zinc finger proteins --- One class of transcription factor proteins containing loop-shaped tandem repeating segments that bind zinc atoms.
本文综述了锌与锌指蛋白的关系以及锌指蛋白对机体贫血的影响，以深入了解机体贫血的机制。
The relationship between zinc and zinc finger protein and effects of zinc finger protein on anemia are reviewed in this article in order to understand the mechanism of anemia.
锌指核酸酶被设计识别基因组特定DNA序列，之后对其进行酶切，进而删除或替换这段序列。
Zinc-finger nucleases are enzymes that can be designed to find specific DNA sequences in the genome and cut them out, deleting those sequences or swapping one gene for another.
我们可以通过对锌指的设计来靶向单个（特定的）基因，与此同时，核酸酶的存在将破坏该基因。
The zinc-finger design allows us to target a single gene, while the nuclease disrupts the gene.
目前正对HIV感染者进行锌指核酸酶临床实验，利用这种酶删除一段使病毒进入免疫细胞的基因。
Clinical trials are underway in HIV patients of zinc-finger nucleases that remove a gene that allows the virus to enter immune cells.
他们团队用利用锌指结构以IPK1基因为目标，另外添加可以中断此基因同时赋予植物抗除草剂性质的细菌DNA序列。
The team used zinc fingers that specifically target the IPK1 gene and then added bacterial DNA that would disrupt the gene while at the same time conferring herbicide resistance to the plant.
锌指核酸酶是一种人工制做限制性内切酶，通过将锌指DNA结合区与限制性内切酶的DNA切割区融合获得。
Zinc finger nucleases (ZFNs) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-binding domain to the DNA cleavage domain of a restriction enzyme.
锌指蛋白是一类广泛存在于原核和真核生物体中的重要转录调控因子，在动植物的生长发育过程中均起着重要作用。
The family of zinc finger proteins is an important member of transcription factors which exists widely in prokaryote and eukaryote.
过去研究人员通过定位这种酶在基因组中的结合位点，之后检测这些序列是否受损的方法来寻找锌指核酸酶的错误。
In the past, researchers have looked for zinc-finger nuclease errors by assaying where in the genome the enzymes might bind, and checking to see whether those sequences were broken.
通过将几个锌指出串联在一起，再加入一个切割dna的核酸酶，研究人员们能够精确地导向将被切割的特异性基因。
Bystringing together several zinc fingers and adding a DNA-cleaving nuclease, researchers can precisely target specific genes to be cut.
通过将几个锌指出串联在一起，再加入一个切割dna的核酸酶，研究人员们能够精确地导向将被切割的特异性基因。
Bystringing together several zinc fingers and adding a DNA-cleaving nuclease, researchers can precisely target specific genes to be cut.
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