结论骨髓间充质干细胞上清可抑制单核细胞来源的树突状细胞的成熟和功能,诱导免疫耐受。
Conclusion Human bone marrow mesenchymal stem cells inhibit maturation and function of monocyte-derived dendritic cells and induce immune tolerance.
树突状细胞(DC)是骨髓来源的专职抗原呈递细胞。
Dendritic cells (DC) are bone marrow-derived professional antigen-presenting cells.
方法:采用脐带血来源的单核细胞制备树突状细胞,体外经s- 180细胞肿瘤相关抗原(TAA)致敏后免疫小鼠,一周后接种s - 180细胞株。
Methods: DCs were derived from cord blood monocytes, then were pulsed by tumor associated antigen (TAA) extracted from human stomach cancer S-180 cell line.
方法:采用脐带血来源的单核细胞制备树突状细胞,体外经s- 180细胞肿瘤相关抗原(TAA)致敏后免疫小鼠,一周后接种s - 180细胞株。
Methods: DCs were derived from cord blood monocytes, then were pulsed by tumor associated antigen (TAA) extracted from human stomach cancer S-180 cell line.
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