组蛋白去乙酰酶抑制剂降低抗原提呈小鼠骨髓来源的树突状细胞的活性。
Histone deacetylase inhibitors decrease the antigen presenting activity of murine bone marrow derived dendritic cells.
结论骨髓间充质干细胞上清可抑制单核细胞来源的树突状细胞的成熟和功能,诱导免疫耐受。
Conclusion Human bone marrow mesenchymal stem cells inhibit maturation and function of monocyte-derived dendritic cells and induce immune tolerance.
目的:探讨改善外周血来源的树突状细胞(DC)体外培养的方法,以促进DC的成熟并提高其递呈抗原和激发特异性免疫反应的能力。
PART I The Improvement of Dendritic Cell Culture Measures in vitroObjective: Improve the measures of dendritic cell culture in vitro, to increase the rate of mature and function of DC.
本文从树突状细胞的来源、分化成熟、抗原提呈机理及抗肿瘤治疗的实验研究、临床应用等方面进行综述。
In this review, we summarize the source, differentiation, antigen presenting mechanism, the experimental and clinical researches on anti tumor therapy of dendritic cells.
目的:探讨体外分离、培养和扩增大鼠骨髓来源树突状细胞(DC)的有效方法。
Objective: To study the effective method of isolation, culture and proliferation of rat bone marrow-derived dendritic cells (DC) in vitro.
树突状细胞(DC)是骨髓来源的专职抗原呈递细胞。
Dendritic cells (DC) are bone marrow-derived professional antigen-presenting cells.
方法:采用脐带血来源的单核细胞制备树突状细胞,体外经s- 180细胞肿瘤相关抗原(TAA)致敏后免疫小鼠,一周后接种s - 180细胞株。
Methods: DCs were derived from cord blood monocytes, then were pulsed by tumor associated antigen (TAA) extracted from human stomach cancer S-180 cell line.
树突状细胞来源的外泌体可诱导抗肿瘤免疫并且已被应用于临床试验鹪[3 -5]。
Dendritic cell-derived exosomes can induce anti-tumor immunity and have been used in clinical trials [3-5].
本文就胸腺内树突状细胞的来源、特点以及在中枢耐受中的机制作一综述。
This review will discuss the origin of mtrathymic DCs and Us mechanisms of inducing immune …
本文就胸腺内树突状细胞的来源、特点以及在中枢耐受中的机制作一综述。
This review will discuss the origin of mtrathymic DCs and Us mechanisms of inducing immune …
应用推荐