FHIT基因是一个近年来发现的新的抑癌基因。
FHIT gene was a new be identified as tumour suppressor gene recently.
相反，未分化癌极少表现出抑癌基因结构的改变。
In contrast, undifferentiated carcinomas rarely exhibit structurally altered tumor suppressor genes.
目的探讨抑癌基因pten蛋白在大肠癌的表达及临床意义。
Objective To explore the expression and clinical significance of PTEN gene in large intestine carcinoma.
作者就目前在脑胶质瘤中研究较多的抑癌基因的进展作了综述。
The advances in the study of tumor suppressor genes in gliomas were reviewed.
从石蜡包埋组织中提取DNA，是进一步研究抑癌基因的基础。
It is the foundation to further research anti-oncogene to extract DNA from paraffin embed constitution.
目的体外构建和表达可调控性人抑癌基因pten重组腺病毒。
Objective to construct and express a recombinant adenovirus vector which can regulate expression of human tumor suppressor gene PTEN.
由于该机制可影响特定抑癌基因的活性，因而与肿瘤形成密切相关。
This mechanism is particularly relevant in cancer since it can interfere with the activity of specific "suppressor" genes.
D5S471和D5S592附近可能存在食管癌的候选抑癌基因。
There probably existed candidate tumor suppressor gene (s) around D5S592 and D5S471.
目的：探讨卵巢癌病变中P16抑癌基因的改变和可能的作用机制。
Objective: To explore the alteration and the possible mechanism of tumor suppressor gene P16 in the progression of ovarian carcinoma.
目的探讨抑癌基因DPC4和PTEN蛋白在大肠癌的表达及临床意义。
Objective To explore the expression and clinical significance of PTEN and DPC4 gene in large intestine carcinoma.
人抑癌基因，其编码的蛋白，含有其的表达载体和由该载体转化的细胞。
Human cancer suppressor gene, protein encoded therein, expression vector containing the same, and cell transformed by the vector.
目的探讨抑癌基因pten在脑胶质瘤组织中的表达情况及其临床意义。
Objective to investigate the expression of tumor suppressor PTEN mRNA in human glioma and to elucidate its clinical significance.
热休克蛋白可能有助于细胞周期调控通过与原癌基因的产品或抑癌基因的产品。
Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
目的：从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array.
而某些癌基因和抑癌基因对HIF-1表达及活性的影响最终决定着肿瘤的预后。
The influencing of some oncogene and anti-oncogene to the expression and activity of HIF-1 determines neoplastic prognosis ultimately.
结论转染野生型PTEN抑癌基因能降低人高转移性黏液表皮样癌细胞转移能力。
Conclusion Transfection of wild-type PTEN tumor suppressor gene might significantly reduce metastatic ability of human highly metastatic mucoepidermoid carcinoma cells.
肿瘤形成与控制细胞生长和分化的多种基因特别是癌基因、抑癌基因的遗传改变有关。
There are multiple genes especially oncogenes and tumor suppressor genes involved in 'the genetic alterations which regulating the growth and differentiation of cells.
原癌基因的激活，抑癌基因的失活、突变，抗细胞凋亡等不同的机制都可能参与其中。
The different mechanisms, such as the activation of oncogenes, the inactivation and mutation of tumor suppressor gene, antiapoptosis and so on are involved in .
目的：研究抑癌基因PTEN在人肝细胞肝癌中的表达及其与HCV核心蛋白间的关系。
Objective: To study the relationship between PTEN expression and HCV core protein in hepatocellular carcinoma (HCC).
近来对新发现的肿瘤转移抑制基因NM 23和抑癌基因pten引起了人们极大关注。
Recently, the new discovered NM23 gene (a tumor metastasis suppressor gene) and PTEN gene (a tumor suppressor gene) cause people's attention extensively.
同样，这个重要的抑癌基因可能在流产中产生了重要的作用，它增加了流产发生的可能性。
They also raise the possibility that this important tumor-suppressor gene might play a role in miscarriages.
肿瘤的发生是原癌基因激活、抑癌基因失活以及凋亡相关基因失调等诸多因素综合作用的结果。
The development of tumor results from complex action among multiple factors such as oncogene activation, anti-oncogene inactivation, disturbance of apoptosis related gene and so on.
胃癌的发生与多基因异常表达密切相关，其中抑癌基因甲基化是胃癌发生、展的重要机制之一。
The genesis of gastric cancer resulted from abnormal expression of many genes, and methylation of the tumor suppressor genes is one of the major mechanisms of gastric carcinogenesis.
我们证明Chd5在活体中作为抑癌基因发挥作用而且在人类恶性肿瘤与CHD5的缺失有关。
We demonstrate that Chd5 functions as a tumor suppressor in vivo and implicate deletion of CHD5 in human cancer.
越来越多的证据表明，肿瘤的发生是多因素作用的结果，与癌基因的激活与抑癌基因的失活有关。
More and more evidence indicated that the formation of tumor is due to multi factors with oncogene activation and anti oncogene inactivation.
癌基因和抑癌基因的发现，细胞信号传导通路的阐明，极大地丰富了人们对细胞癌变机制的认识。
The discovery of oncogenes and tumor suppressor genes, and the research of signal transduction pathway yield profound insights into the mechanisms of carcinogenesis.
研究表明几乎一半人类肿瘤都存在抑癌基因的失活，可见抑癌基因失活与肿瘤生长有着密切的关系。
Studies have sh own that the anti oncogene inactivation was closely related to tumor development because of the findings of anti oncogene inactivation in nearly one half of human tumors.
研究肺癌抑癌基因1 (TSLC1)对人前列腺癌t 3 B细胞侵袭、成瘤和转移能力的影响。
To investigate the effects of tumor suppressor in lung cancer-1 (TSLC1) on cell aggression, tumor formation and capability of metastasis in human prostatic carcinoma cell line T3B.
研究肺癌抑癌基因1 (TSLC1)对人前列腺癌t 3 B细胞侵袭、成瘤和转移能力的影响。
To investigate the effects of tumor suppressor in lung cancer-1 (TSLC1) on cell aggression, tumor formation and capability of metastasis in human prostatic carcinoma cell line T3B.
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