“从不吸烟的患者对一类叫表皮生长因子受体抑制剂的药物反应更好,因为这类患者有表皮生长因子受体基因突变的可能性更大一些。”鲁丁说。
"Patients who never smoked respond better to a certain class of drugs called EGFR inhibitors, because lung cancer in these patients more often contain mutations in the EGFR gene," Rudin says.
由于移植物抗宿主病病情的严重性,临床医生在治疗中,往往缺乏细致诊断,就使用大剂量的类固醇抑制免疫细胞的反应。
Because of the severity of GVHD, clinicians often begin treatment — high doses of steroids to suppress the immune response — in the absence of a concrete diagnosis.
设计该药物能够选择性抑制糖代谢相关蛋白而不作用与其他生物反应密切相关蛋白。
The medicine was designed to selectively inhibit the protein associated with glucose metabolism but not other closely related proteins that are associated with other biologic activity.
通过往锌池中加入一定的镍或者提高镀锌温度,可以在一定程度上抑制硅的反应性,但机理不清楚。
The adding of ni into the zinc bath or increasing of the galvanizing temperature can inhibit the reactivity partially. But the mechanism is not well understood.
目的观察环氧酶抑制剂对胆囊切除术后创伤性应激反应的影响。
Objective To study the effect of cyclo-oxygenase inhibitor (indocontin) on traumatic stress response of patients undergoing cholecystectomy.
用生物检定法评价两者对致敏豚鼠肺组织抗原攻击释放过敏性慢反应物质(SRS-A)的抑制作用;
Slow reaction substance of anaphylaxis(SRS-A) release from lung tissues of the sensitized guinea pigs after antigen challenge was examined by bioassay.
抑制控制能力是指个体为实现特定目标对干扰性优势反应进行抑制的能力,是一种高级认知能力。
Inhibitory control is a high-order cognitive ability which is to inhibit the interferential prepotent response in order to achieve a specific goal.
抑制性影响使下丘听神经元的频率调谐曲线变窄,听空间反应区域缩小,易化性影响与之相反。
Corticofugal inhibition sharpened the frequency tuning and reduced the auditory response area of IC neurons, and corticofugal facilitation produced the opposite effects.
返回抑制是指对先前注意的位置上进行反应所表现出的滞后现象,是选择性注意的一个重要现象。
Inhibition of Return (IOR) is the hysteresis phenomenon shown by the reaction of the previous note on the location and it is a significant phenomenon to selective attention.
目的以谷胱甘肽-S -转硫酶(GST)为模型,探讨有产物抑制时用积分法分析酶反应过程测定底物量的可靠性。
Objective To investigate the reliability of the integrated method for kinetic assay of substrate in the presence of product inhibition using glutathione-S-transferase (GST) as model.
结论:视神经间接损伤后,早期适量的X射线局部照射能有效地抑制胶质细胞的反应性增生,能明显地促进神经轴突的结构再生。
It is suggested that early proper X-ray irradiation on the injured optic nerve can effectively inhibit the proliferation of astrocytes and obviously promote the axonal regeneration of optic nerve.
结果:辅助性肝脏移植患者免疫抑制剂浓度相对较低,排斥反应次数少,强度低。
Results:Immunosuppressive agent concentration was lower, rejection was less and intensity was milder in these patients.
以稳定运行的全程硝化的生物膜反应器的一个反应单元为研究对象,通过外加氯实现对硝化反应中两类细菌的选择性抑制。
In a cell of biofilm reactor for whole-run nitrification, chlorine was added to achieve the selective inhibition to two kinds of bacteria in nitrification.
布洛芬抑制前列腺素的生成,并通过增强缺氧性肺血管收缩反应而改善了肺损伤时的气体交换。
The inhibition of prostaglandin production with Ibuprofen strengthened hypoxic pulmonary vasoconstriction thus improved pulmonary gas exchanges in acid lung injury.
另外,科研人员应继续开发和利用新型共刺激靶点及免疫抑制剂,这可能对消除记忆性T细胞的反应有关键作用。
Additionally, research efforts should continue to identify and manipulate new costimulatory targets and immunosuppressants, which may be key to abrogating memory T-cell responses.
结论异种移植发生延迟性排斥反应时,P选择素和ICAM - 1均有表达,可以作为判断异种移植免疫抑制治疗效果的指标之一。
Conclusion the expression of P-selectin and ICAM-1 in xenografts was increased during delayed xenograft rejection, which is of value in judging the effect of immunosuppression in xenotransplantation.
近年来,调节性T细胞在自身耐受和抑制同种异体排斥反应中的作用受到越来越多的重视。
Recently, accumulating evidences have shown that regulatory t cells play a key role both in maintenance of self tolerance and tolerance to allograft.
目的观察血管紧张素转化酶抑制药卡托普利对大鼠局灶性脑缺血再灌注损伤后炎症反应的影响。
Purpose to investigate the anti-inflammatory effect of angiotensin-converting enzyme inhibitor captopril on the brain against ischemia-reperfusion injury and explore its mechanism of action.
结论TMP主要通过抑制P 2 X受体兴奋介导的伤害性信息传递产生抗伤害性反应作用。
Conclusion the antinociceptive effects of TMP may mainly be associated with inhibiting the transmission of nociceptive information mediated by P2X receptor activation.
它们是损伤后轴索反应性生长的天然抑制物。
They serve as natural impediments to neurite growth in response to injury.
目的:探讨氧化苦参碱(omt)对小鼠变态反应性接触性皮炎(ACD)的抑制作用。
Aim: To explore the inhibitive effects of oxymatrine (OMT) on allergic contact dermatitis (ACD) in mice.
目的:评价大黄素抗脑缺血损伤作用,并从细胞因子水平及表达方面探讨其抑制炎性级联反应机制。
Objective: to assess emodin antagonism to cerebral ischemia injury, and to discuss the mechanism of emodin inhibiting the inflammatory cascade reaction from the levels and expressions of cytokines.
说明消瘀止痛膏具有抑制创伤局部无菌性炎症反应、降低血液粘度、改善微循环、促进伤区血肿吸收和组织修复的作用。
It was suggested that it could inhibit aseptic inflammatory reaction reduce the blood viscosity, improve blood circulation and benefit the repairing of soft tissue.
目的:观察代偿性心脏增大大鼠心肌肥厚过程中各种炎症反应标记物的动态变化及特异性环氧化酶-2抑制剂的影响。
Objective:To investigate the change of inflammation marker in the development of rats with pressure overloaded hypertrophy myocardium and influence of selective cyclooxygenase-2 inhibitor.
建立了固定化纤维素酶的反应动力学模型,该模型以米氏方程为基础并考虑了产物竞争性抑制的影响。
A kinetics model was developed for predicting and simulating immobilized cellulase performance, which follows Michaelis_Menten kinetics with competitive product inhibition.
结果发现:海马脑片缺氧早期突触功能出现可逆性抑制,与外源施加高浓度腺苷反应类同。
The results showed that acute anoxia led to the reversible inhibition of synaptic function, which is similar to the response to addition of high concentration of exogenous adenosine.
结果表明:燃料温度变化相对于功率的变化缓慢且滞后,燃料温度反应性负反馈不能及时抑制功率的变化是形成系统参量产生衰减振荡的主要原因。
The results indicate that fuel temperature changing more slowly than nuclear power makes reactivity negative feedback not to restrain power changing, and then power concussive progress comes to being.
因此本文对气质社会抑制性和执行性注意这两种执行性和反应性抑制进行区分并探讨他们之间的关系。
Thus the aim of the present thesis is to investigate the possible relationships between social inhibition of temperament and executive attention.
应用氯代酚类中的2,4 -二氯酚(2,4 -DCP)对好氧微生物呼吸反应作抑制性试验。
The article describes the inhibitory experiment which the aerobic microorganism breathing responds to one kind of chlorophenol compounds named 2, 4-double chlorophenol (2, 4-dcp).
结论:缬沙坦可能是通过抑制AT 1受体抑制哮喘气道炎症和降低气道反应性。
Conclusion: Valsartan may inhibit airway inflammation and reduce airway responsiveness by suppressing AT1 receptors.
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