目的：探讨主动外排泵在嗜麦芽寡养单胞菌对氟喹诺酮类药物耐药中的作用。
Objective:To explore the role of efflux pump in drug resistance to fluoroquinolones in Stenotrophomonas maltophilia.
主动外排机制不仅存在于FQNS耐药菌株，而且也存在于FQNS敏感菌株。
Active efflux mechanism exist not only in FQNS resistant strains, but also in FQNS susceptible strains.
目的：研究临床分离的大肠杆菌多重耐药株和敏感株中抗菌药物的主动外排系统。
ABSTRACT Objective: To investigate active efflux of drugs in clinical isolated strains of Escherichia coli.
肠球菌对氟喹诺酮类抗菌药的耐药机制主要为靶位改变和药物主动外排导致的细胞内药物积聚减少。
The main two mechanisms of FQs resistance in enterococci are alterations in the targets of FQs and decreased intra-cellular drugs accumulation resulting from active excretion of drug.
用逆转录-聚合酶链反应(RT - PCR)方法检测主动外排泵基因CDR1和CDR2的表达水平。
Reverse transcriptase-polymerase chain reaction (RT-PCR) was used to measure the mRNA levels of active efflux gene CDR1 and CDR2.
用逆转录-聚合酶链反应(RT - PCR)方法检测主动外排泵基因CDR1和CDR2的表达水平。
Reverse transcriptase-polymerase chain reaction (RT-PCR) was used to measure the mRNA levels of active efflux gene CDR1 and CDR2.
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