Objective: To prepare Paeonol Sustained-release Tablets of zero order release.
目的：制备具零级释药特征的丹皮酚缓释片。
The pattern of drug release for 30 days in vitro fitted to zero order release plot, with an initial burst effect at the first day.
体外释放第一天呈突释效应，而后药物释放基本符合零级动力学过程。
Conclusions: The ambroxol HCl osmotic pump controlled release tablets have a stable release curve and conform to zero release order.
结论：盐酸氨溴索渗透泵控释片释药稳定，零级释药明显，具备优良控释制剂的特征。
The research of in vitro release indicates that the two drugs of preparation both can reach the zero-order release.
体外释放研究表明制剂中两种药物均可达到零级释放。
Conclusions: the osmotic pump tablets conform to zero release order in 14 hours, and within the following dose reduction in osmotic pump, the release rate has declined.
结论：本制剂在14h内呈现良好的零级释药特征，此后随渗透泵内药量的减少，释放速度有所下降。
The system of multi-layered matrix tablets provided an effective method for zero-order release of highly soluble drugs.
因此，多层骨架片系统是制备高水溶性药物控释制剂的有效方法。
Results The pharmacokinetics of the non-parenteral administration of the zero-order release and the first-order release of mono-compartment drugs were established.
结果得到了零级释放和一级释放在释放期间和释放结束后的血药动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
Conclusion the pharmacokinetic theories of the zero-order release and the first-order release of mono-compartment drugs administered by non-parenteral route have been established.
结论建立了单室模型药物血管外给药零级释放和一级释放的药物动力学。
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