There were 35 embryonal carcinomas, 11 teratomas, 3 yolk sac tumors, 6 choriocarcinomas and 13 mixed germ cell tumors.
胚胎癌35例，畸胎瘤11例，卵黄囊瘤3例，绒毛膜上皮癌6例，混合性生殖细胞瘤13例。
Objective: malignant germ cell tumors occur in childhood at a rate of 2 to 3 cases per million children, and Yolk sac tumor accounts for the most (62.7%) of malignant germ cell tumors.
目的：儿童恶性生殖细胞肿瘤的发病率是百万分之二到三，卵黄囊瘤是其中最常见的儿童恶性生殖细胞肿瘤，约占62.7%。
ConclusionATRA could inhibit proliferation of yolk sac tumor cell line, and down regulation of VEGF could be the inhibitory mechanism of ATRA on yolk sac tumor cell line in vitro.
结论全反式维甲酸可以抑制睾丸卵黄囊瘤细胞的增殖，抑制肿瘤增殖机制可能与下调VEGF的表达有关。
ConclusionATRA could inhibit proliferation of yolk sac tumor cell line, and down regulation of VEGF could be the inhibitory mechanism of ATRA on yolk sac tumor cell line in vitro.
结论全反式维甲酸可以抑制睾丸卵黄囊瘤细胞的增殖，抑制肿瘤增殖机制可能与下调VEGF的表达有关。
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