Objective To analyze mutations in the Wilms tumor gene (WT1) in Ieukemogenesis.
目的瘤基因(WT1)突变与白血病发病的关系。
P53 and WT1 are negative in most cases or weakly focally positive in few cases.
P 53和WT1在大多数病例中为阴性表达，少数病例中可见一些叫弱的或局灶性阳性表达。
The overexpression of WT1 might be the molecular marker for the epithelial ovarian carcinoma.
WT 1异常高表达可能是诊断卵巢癌的分子标志物。
Objective: To study the expression of MUC1 and WT1 gene in acute leukemia and their clinical significance.
目的：探讨MUC1基因及WT 1基因在急性白血病的表达及临床意义。
Objective: To elucidate the expression of Wilms' tumor gene (WT1) in leukemias and its clinical implication.
目的：探讨WT 1基因在白血病细胞中的表达及其临床意义。
Conclusion: (1) WT1 has different expressions in different histologic subtypes of primary ovarian carcinomas.
结论WT 1在不同亚型上皮性卵巢癌中表达不同。
The WT1 expression level of chronic myeloid leukemia (CML) in blast crisis was higher than that of CML in chronic phase.
慢性髓性白血病(CML)急变期患者WT 1基因表达水平显著高于慢性期。
Objective: To evaluate the relationship between WT1 and LRP genes expression and their prognostic value in acute leukemia.
目的：探讨急性白血病患者WT 1基因与LRP基因表达的关系。
Objective:To explore the expression and significance of the WT1 gene and proteins in patients with acute myelocytic leukemia(AML).
目的：探讨WT1基因及其蛋白产物在急性髓细胞白血病（AML）细胞的表达及临床意义。
All people with WAGR syndrome lack two specific genes, called WT1 and PAX6, but each person can also be missing other nearby genes.
所有患有WAGR综合症的患者都缺少两个称为WT1和PAX6的基因，但是每一个个体也可以丢失其它附近的基因。
Methods: Expressions of WT1 and LRP genes were measured in 73 patients with acute leukemia and 23 normal controls by RT-PCR method.
方法：应用逆转录-聚合酶链反应(RT - pcr)法检测73例急性白血病患者及23例正常人的WT 1及LRP基因的表达。
Conclusion Monitoring of the WT1 gene by Nest RTPCR would be a surely marker for the detection of minimal residual disease (MRD) in acute leukemia.
结论用Nest、RT - PCR测定WT 1基因的表达可作为检测白血病微小残留病(MRD)的一项指标。
In conclusion, bortezomib used alone in MDS shows modest hematologic efficacy but appears to affect the WT1 gene expression, which is typically increased in these diseases.
总之，单独使用硼替佐米治疗MDS显示出一定的血液学效果但可能影响WT 1基因表达，WT1的增高在这些疾病中具有典型性。
Method The expression of WT1 gene and its DNA methylation status were assayed in leukemia cell lines and normal peripheral blood mononuclear cells (PBMNC) by RT-PCR and MS-PCR.
方法采用RT P CR技术、硫化pcr结合限制性内切酶技术检测白血病细胞系及正常人外周血单个核细胞WT 1基因的表达及其启动子区DNA甲基化水平。
None was WT1 positive in peripheral blood mononuclear cells (MNC) from 29 blood donors, while bone marrow MNCs from eight of 21 cases (38.1%) of nonmalignant patient WT1 gene expression were found.
在2 9例供血员的外周血单个核细胞（MNC）均未检测到WT1基因表达，但在2 1例非恶性疾病患者骨髓MNC中有8例呈WT1基因阳性（38.1% ）。
None was WT1 positive in peripheral blood mononuclear cells (MNC) from 29 blood donors, while bone marrow MNCs from eight of 21 cases (38.1%) of nonmalignant patient WT1 gene expression were found.
在2 9例供血员的外周血单个核细胞（MNC）均未检测到WT1基因表达，但在2 1例非恶性疾病患者骨髓MNC中有8例呈WT1基因阳性（38.1% ）。
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