Further studies will examine the relationship among the Notch, Hedgehog and Wnt pathways in glioblastoma and look for other signaling processes that help tumors become resistant to therapy, he says.
更深入的研究将会阐释恶性胶质瘤中NotchHedgehog和Wnt通路之间的关系，并寻找使肿瘤产生耐药性的其他信号传导途径，他说。
In our effort to understand how Wnt signaling exerts its influence on HSCs, we discovered that some transcriptional targets of the Notch pathway were upregulated by Wnt signaling.
我们在努力弄明白Wnt信号是怎样影响造血干细胞的时候，我们发现一些Notch通路的转录结果因Wnt信号被上调了。
We observed a widespread oscillatory-like pattern of changes in gene expression, involving components of both the canonical and the noncanonical Wnt signaling pathways.
我们看到一个广泛的oscillatory - like模式的变化，包括组件进行基因表达两种典型和经典之中Wnt信号传导通路。
That signaling pathways such as Bmi1 and Wnt have similar effects in normal and cancer stem cell self-renewal suggests that common molecular pathways regulate both populations.
bmi1和wnt等信号信号通路在正常及肿瘤干细胞的自我更新中有类似的效果提示这一共同的分子途径可以调节两者的作用。
That signaling pathways such as Bmi1 and Wnt have similar effects in normal and cancer stem cell self-renewal suggests that common molecular pathways regulate both populations.
bmi1和wnt等信号信号通路在正常及肿瘤干细胞的自我更新中有类似的效果提示这一共同的分子途径可以调节两者的作用。
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